Photodynamic bioassay of benzo(a)pyrene with Paramecium caudatum

Journal Article · Mon Jul 01 00:00:00 EDT 1963 · J. Natl. Cancer Inst.; (United States)

OSTI ID:5310513

Epstein, S S; Small, M; Koplan, J; Mantel, N; Hutner, S H

The photodynamic toxicity of benzo(a)pyrene (BaP) to Paramecium caudatum and a variety of other in vivo systems is well established. Recent improvements in the culture of P. caudatum have facilitated standardization of the photodynamic response. A simple bioassay procedure, based on this response, was developed as a preliminary to the assay for photodynamic toxicity of crude organic extracts, such as atmospheric pollutants.

• Research Organization: Children's Cancer Research Foundation, Boston, MA
• OSTI ID: 5310513
• Journal Information: J. Natl. Cancer Inst.; (United States), Vol. 31:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BENZOPYRENE
BIOASSAY
TOXICITY
EXPERIMENTAL DATA
PARAMECIUM
PHOTOCHEMICAL OXIDANTS
ANIMALS
AROMATICS
CILIATA
CONDENSED AROMATICS
DATA
HYDROCARBONS
INFORMATION
INVERTEBRATES
MICROORGANISMS
NUMERICAL DATA
ORGANIC COMPOUNDS
PROTOZOA
560302* - Chemicals Metabolism & Toxicology- Microorganisms- (-1987)