I-131 rose bengal excretion test is not dead
One hundred and thirty I-131 Rose Bengal Excretion Studies (RBI) were performed on 84 patients over nine years. In 90% (56/60) of cases with biliary atresia, the 72-hour RBI was less than or equal to 7%. In only 12.5% (3/24) of cases with neonatal hepatitis was the 72-hour RBI less than or equal to 7%. The accuracy of the test was 91% with a specificity of 88%. Thirty patients later were studied following a Kasai procedure. The RBI test reliably predicted the patency of the anastomosis. The authors conclude that the 72-hour RBI is a reliable test in the diagnosis of biliary atresia and in the documentation of biliary patency following surgery, provided adequate care is taken in stool collection and measurement.
- Research Organization:
- Hospital for Sick Children, Toronto, Ontario
- OSTI ID:
- 5266073
- Journal Information:
- Clin. Nucl. Med.; (United States), Vol. 3
- Country of Publication:
- United States
- Language:
- English
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Cholestatic syndromes in infancy and childhood
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DIAGNOSTIC TECHNIQUES
EVALUATION
HEPATITIS
DIAGNOSIS
ACCURACY
EXCRETION
IODINE 131
PATIENTS
ROSE BENGAL
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CARBOXYLIC ACIDS
CLEARANCE
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM DISEASES
DISEASES
DYES
HYDROXY ACIDS
INDICATORS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC IODINE COMPOUNDS
RADIOISOTOPES
REAGENTS
550901* - Pathology- Tracer Techniques