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Title: Gene expression: The missing link in evolutionary computation

Abstract

This paper points out that the traditional perspective of evolutionary computation may not provide the complete picture of evolutionary search. This paper focuses on gene expression-- transformations of representation (DNA->RNA->Protein) from a the perspective of relation construction. It decomposes the complex process of gene expression into several steps, namely (1) expression control of DNA base pairs, (2) alphabet transformations during transcription and translation, and (3) folding of the proteins from sequence representation to Euclidean space. Each of these steps is investigated on grounds of relation construction and search efficiency. At the end these pieces of the puzzle are put together to develope a possibly crude and cartoon computational description of gene expression.

Authors:
Publication Date:
Research Org.:
Los Alamos National Lab., NM (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
524858
Report Number(s):
LA-UR-97-2842; CONF-970740-4
ON: DE97008326
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Conference
Resource Relation:
Conference: 7. international conference on genetic algorithms, Lansing, MI (United States), 19 Jul 1997; Other Information: PBD: [1997]
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; 99 MATHEMATICS, COMPUTERS, INFORMATION SCIENCE, MANAGEMENT, LAW, MISCELLANEOUS; GENE REGULATION; BIOLOGICAL EVOLUTION; MATHEMATICAL MODELS; PROTEIN STRUCTURE; MATRIX ISOLATION; ALGORITHMS

Citation Formats

Kargupta, H. Gene expression: The missing link in evolutionary computation. United States: N. p., 1997. Web.
Kargupta, H. Gene expression: The missing link in evolutionary computation. United States.
Kargupta, H. Mon . "Gene expression: The missing link in evolutionary computation". United States. https://www.osti.gov/servlets/purl/524858.
@article{osti_524858,
title = {Gene expression: The missing link in evolutionary computation},
author = {Kargupta, H.},
abstractNote = {This paper points out that the traditional perspective of evolutionary computation may not provide the complete picture of evolutionary search. This paper focuses on gene expression-- transformations of representation (DNA->RNA->Protein) from a the perspective of relation construction. It decomposes the complex process of gene expression into several steps, namely (1) expression control of DNA base pairs, (2) alphabet transformations during transcription and translation, and (3) folding of the proteins from sequence representation to Euclidean space. Each of these steps is investigated on grounds of relation construction and search efficiency. At the end these pieces of the puzzle are put together to develope a possibly crude and cartoon computational description of gene expression.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Sep 01 00:00:00 EDT 1997},
month = {Mon Sep 01 00:00:00 EDT 1997}
}

Conference:
Other availability
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