Chronic effects of mercuric chloride on the activities of some enzymes in certain tissues of the fresh water murrel, Channa punctatus
Alterations in the activities of some enzymes in the brain, gills, intestine, kidney, liver and muscles have been examined in the fresh water mercuric chloride (3 ..mu..g/l) for 15, 30, and 60 days. The results revealed that after 15 days of exposure amino acid oxidase activity was elevated in brain and liver and inhibited in intestine. The activity of xanthine oxidase was increased in gills, and inhibited in kidney. Thirty days exposure in liver, glutamate dehydrogenase in gills and brain, aminoacid oxidase in liver and intestine. In contrast, glutamate dehydrogenase in intestine, kidney and liver and aminoacid oxidase in brain and liver were elevated. After 60 days of treatment, a decrease in the activity of glucose-6-phosphatase was recorded in gills, intestine, kidney and liver. Hexokinase activity in kidney and liver, and malate dehydrogenase in all the six tissues were inhibited. Glutamate dehydrogenase activity in intestine, kidney and liver remained higher than in control fish. In brain, kidney and liver the activity of aminoacid oxidase was elevated, but in gills the enzyme activity decreased. Xanthine oxidase activity was inhibited in intestine and liver.
- Research Organization:
- Environmental Toxicology Lab., Muzaffarnagar, India
- OSTI ID:
- 5233265
- Journal Information:
- Chemosphere; (United States), Vol. 11:12
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
FISHES
ENZYME ACTIVITY
MERCURY CHLORIDES
BIOLOGICAL EFFECTS
CHRONIC EXPOSURE
OXIDOREDUCTASES
BIOCHEMISTRY
BRAIN
EXPERIMENTAL DATA
GILLS
INTESTINES
KIDNEYS
LIVER
MUSCLES
ANIMALS
AQUATIC ORGANISMS
BODY
CENTRAL NERVOUS SYSTEM
CHEMISTRY
CHLORIDES
CHLORINE COMPOUNDS
DATA
DIGESTIVE SYSTEM
ENZYMES
GASTROINTESTINAL TRACT
GLANDS
HALIDES
HALOGEN COMPOUNDS
INFORMATION
MERCURY COMPOUNDS
MERCURY HALIDES
NERVOUS SYSTEM
NUMERICAL DATA
ORGANS
RESPIRATORY SYSTEM
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
550200 - Biochemistry