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Title: Chronic effects of mercuric chloride on the activities of some enzymes in certain tissues of the fresh water murrel, Channa punctatus

Abstract

Alterations in the activities of some enzymes in the brain, gills, intestine, kidney, liver and muscles have been examined in the fresh water mercuric chloride (3 ..mu..g/l) for 15, 30, and 60 days. The results revealed that after 15 days of exposure amino acid oxidase activity was elevated in brain and liver and inhibited in intestine. The activity of xanthine oxidase was increased in gills, and inhibited in kidney. Thirty days exposure in liver, glutamate dehydrogenase in gills and brain, aminoacid oxidase in liver and intestine. In contrast, glutamate dehydrogenase in intestine, kidney and liver and aminoacid oxidase in brain and liver were elevated. After 60 days of treatment, a decrease in the activity of glucose-6-phosphatase was recorded in gills, intestine, kidney and liver. Hexokinase activity in kidney and liver, and malate dehydrogenase in all the six tissues were inhibited. Glutamate dehydrogenase activity in intestine, kidney and liver remained higher than in control fish. In brain, kidney and liver the activity of aminoacid oxidase was elevated, but in gills the enzyme activity decreased. Xanthine oxidase activity was inhibited in intestine and liver.

Authors:
;
Publication Date:
Research Org.:
Environmental Toxicology Lab., Muzaffarnagar, India
OSTI Identifier:
5233265
Resource Type:
Journal Article
Journal Name:
Chemosphere; (United States)
Additional Journal Information:
Journal Volume: 11:12
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; FISHES; ENZYME ACTIVITY; MERCURY CHLORIDES; BIOLOGICAL EFFECTS; CHRONIC EXPOSURE; OXIDOREDUCTASES; BIOCHEMISTRY; BRAIN; EXPERIMENTAL DATA; GILLS; INTESTINES; KIDNEYS; LIVER; MUSCLES; ANIMALS; AQUATIC ORGANISMS; BODY; CENTRAL NERVOUS SYSTEM; CHEMISTRY; CHLORIDES; CHLORINE COMPOUNDS; DATA; DIGESTIVE SYSTEM; ENZYMES; GASTROINTESTINAL TRACT; GLANDS; HALIDES; HALOGEN COMPOUNDS; INFORMATION; MERCURY COMPOUNDS; MERCURY HALIDES; NERVOUS SYSTEM; NUMERICAL DATA; ORGANS; RESPIRATORY SYSTEM; VERTEBRATES; 560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987); 550200 - Biochemistry

Citation Formats

Sastry, K V, and Rao, D R. Chronic effects of mercuric chloride on the activities of some enzymes in certain tissues of the fresh water murrel, Channa punctatus. United States: N. p., 1982. Web.
Sastry, K V, & Rao, D R. Chronic effects of mercuric chloride on the activities of some enzymes in certain tissues of the fresh water murrel, Channa punctatus. United States.
Sastry, K V, and Rao, D R. Fri . "Chronic effects of mercuric chloride on the activities of some enzymes in certain tissues of the fresh water murrel, Channa punctatus". United States.
@article{osti_5233265,
title = {Chronic effects of mercuric chloride on the activities of some enzymes in certain tissues of the fresh water murrel, Channa punctatus},
author = {Sastry, K V and Rao, D R},
abstractNote = {Alterations in the activities of some enzymes in the brain, gills, intestine, kidney, liver and muscles have been examined in the fresh water mercuric chloride (3 ..mu..g/l) for 15, 30, and 60 days. The results revealed that after 15 days of exposure amino acid oxidase activity was elevated in brain and liver and inhibited in intestine. The activity of xanthine oxidase was increased in gills, and inhibited in kidney. Thirty days exposure in liver, glutamate dehydrogenase in gills and brain, aminoacid oxidase in liver and intestine. In contrast, glutamate dehydrogenase in intestine, kidney and liver and aminoacid oxidase in brain and liver were elevated. After 60 days of treatment, a decrease in the activity of glucose-6-phosphatase was recorded in gills, intestine, kidney and liver. Hexokinase activity in kidney and liver, and malate dehydrogenase in all the six tissues were inhibited. Glutamate dehydrogenase activity in intestine, kidney and liver remained higher than in control fish. In brain, kidney and liver the activity of aminoacid oxidase was elevated, but in gills the enzyme activity decreased. Xanthine oxidase activity was inhibited in intestine and liver.},
doi = {},
url = {https://www.osti.gov/biblio/5233265}, journal = {Chemosphere; (United States)},
number = ,
volume = 11:12,
place = {United States},
year = {1982},
month = {1}
}