Role of DNA polymerase I-associated 5'-exonuclease in replication of coliphage M13 replicative-form DNA
Abstract
The conversion of both parental- and progeny-nascent open circular M13 RF DNA into covalently closed RF I is drastically reduced in an E. coli mutant deficient in the 5' ..-->.. 3' exonuclease associated with DNA polymerase I. The nascent progeny RF DNA also contains a significant proportion of fragments of smaller than unit length.
- Authors:
- Publication Date:
- Research Org.:
- Oak Ridge National Lab., TN
- OSTI Identifier:
- 5206622
- Resource Type:
- Journal Article
- Journal Name:
- Biochem. Biophys. Res. Commun.; (United States)
- Additional Journal Information:
- Journal Volume: 78:3
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; DNA REPLICATION; BIOCHEMISTRY; CHEMICAL REACTIONS; DNA; ENZYMES; ESCHERICHIA COLI; MUTANTS; POLYMERASES; STRAND BREAKS; BACTERIA; CHEMISTRY; MICROORGANISMS; NUCLEIC ACID REPLICATION; NUCLEIC ACIDS; ORGANIC COMPOUNDS; 550300* - Cytology
Citation Formats
Dasgupta, S, and Mitra, S. Role of DNA polymerase I-associated 5'-exonuclease in replication of coliphage M13 replicative-form DNA. United States: N. p., 1977.
Web. doi:10.1016/0006-291X(77)90535-6.
Dasgupta, S, & Mitra, S. Role of DNA polymerase I-associated 5'-exonuclease in replication of coliphage M13 replicative-form DNA. United States. https://doi.org/10.1016/0006-291X(77)90535-6
Dasgupta, S, and Mitra, S. 1977.
"Role of DNA polymerase I-associated 5'-exonuclease in replication of coliphage M13 replicative-form DNA". United States. https://doi.org/10.1016/0006-291X(77)90535-6.
@article{osti_5206622,
title = {Role of DNA polymerase I-associated 5'-exonuclease in replication of coliphage M13 replicative-form DNA},
author = {Dasgupta, S and Mitra, S},
abstractNote = {The conversion of both parental- and progeny-nascent open circular M13 RF DNA into covalently closed RF I is drastically reduced in an E. coli mutant deficient in the 5' ..-->.. 3' exonuclease associated with DNA polymerase I. The nascent progeny RF DNA also contains a significant proportion of fragments of smaller than unit length.},
doi = {10.1016/0006-291X(77)90535-6},
url = {https://www.osti.gov/biblio/5206622},
journal = {Biochem. Biophys. Res. Commun.; (United States)},
number = ,
volume = 78:3,
place = {United States},
year = {Mon Oct 10 00:00:00 EDT 1977},
month = {Mon Oct 10 00:00:00 EDT 1977}
}
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