Liver cysts in autosomal-dominant polycystic kidney disease: clinical and computed tomographic study

Conference · Thu Aug 01 00:00:00 EDT 1985 · AJR, Am. J. Roentgenol.; (United States)

OSTI ID:5149955

Levine, E; Cook, L T; Grantham, J J

Hepatic CT findings were analyzed in 44 patients with autosomal-dominant polycystic kidney disease and were correlated with liver and renal function tests and liver, splenic, and renal CT volume measurements. CT showed many large liver cysts in 31.8% of patients, small liver cysts in 25%, and no liver cysts in 43.2%. Patients with many large cysts often showed increased liver volumes. There was no correlation between severity of liver involvement and extent of renal cystic disease as determined from urea nitrogen and creatinine levels and renal volumes. Liver function tests were normal except in two patients, one with a cholangiocarcinoma, which may have arisen from a cyst, and the other with an infected liver cyst and chronic active hepatitis. Accordingly, if liver function tests are abnormal, an attempt should be made to identify complications of polycystic liver disease such as tumor cyst infection, and biliary obstruction. CT is a useful method for detecting liver cysts and identifying patients at risk for these complications.

• Research Organization: Univ. of Kansas College of Health Sciences, Kansas City
• OSTI ID: 5149955
• Report Number(s): CONF-860416-; TRN: 85-023784
• Journal Information: AJR, Am. J. Roentgenol.; (United States), Vol. 145:2; Conference: ARRS meeting, Washington, DC, USA, 14 Apr 1986
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
KIDNEYS
HEREDITARY DISEASES
LIVER
ABSCESSES
BIOLOGICAL FUNCTIONS
COMPUTERIZED TOMOGRAPHY
UROGENITAL SYSTEM DISEASES
DIAGNOSIS
BILIARY TRACT
NEOPLASMS
PATIENTS
VOLUME
BODY
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
FUNCTIONS
GLANDS
ORGANS
PATHOLOGICAL CHANGES
TOMOGRAPHY
550602* - Medicine- External Radiation in Diagnostics- (1980-)