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Title: 5. 8 GHz ophthalmic microwave applicator for treatment of choroidal melanoma

Abstract

We report on the use of a 5.8 GHz microwave applicator to treat choroidal melanoma (Greene) in rabbits. The physical requirements needed to treat these intraocular tumors are quite different from those encountered elsewhere in the body. From a trans-scleral approach the penetration needed is minimal (5 to 10 mm.). The fibrous sclera is the only structure between the heat source and the tumor. The sclera has a relatively low water content when compared to tumor. This fact in addition to the frequency dependent interactions of tissue and electromagnetic radiation, results in an advantage to the use of the 5.8 GHz microwave device in treating intraocular malignancies.

Authors:
; ; ; ; ;
Publication Date:
Research Org.:
Brookhaven National Lab., Upton, NY (USA); RCA Labs., Princeton, NJ (USA). David Sarnoff Research Center; Massachusetts Eye and Ear Infirmary, Boston (USA). Howe Lab. of Ophthalmology
OSTI Identifier:
5125529
Report Number(s):
BNL-33239; CONF-8306184-1
ON: DE84007696
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Conference
Resource Relation:
Conference: IEEE microwave symposium, Boston, MA, USA, 1 Jun 1983; Other Information: Portions are illegible in microfiche products
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; MELANOMAS; HYPERTHERMIA; MICROWAVE EQUIPMENT; DESIGN; EYES; RABBITS; ANIMALS; BODY; BODY AREAS; BODY TEMPERATURE; DISEASES; ELECTRONIC EQUIPMENT; EQUIPMENT; FACE; HEAD; MAMMALS; NEOPLASMS; ORGANS; SENSE ORGANS; VERTEBRATES; 560400* - Other Environmental Pollutant Effects; 550600 - Medicine

Citation Formats

Finger, P T, Packer, S, Svitra, P, Paglione, R W, Albert, D M, and Chess, J. 5. 8 GHz ophthalmic microwave applicator for treatment of choroidal melanoma. United States: N. p., 1983. Web.
Finger, P T, Packer, S, Svitra, P, Paglione, R W, Albert, D M, & Chess, J. 5. 8 GHz ophthalmic microwave applicator for treatment of choroidal melanoma. United States.
Finger, P T, Packer, S, Svitra, P, Paglione, R W, Albert, D M, and Chess, J. Sat . "5. 8 GHz ophthalmic microwave applicator for treatment of choroidal melanoma". United States. https://www.osti.gov/servlets/purl/5125529.
@article{osti_5125529,
title = {5. 8 GHz ophthalmic microwave applicator for treatment of choroidal melanoma},
author = {Finger, P T and Packer, S and Svitra, P and Paglione, R W and Albert, D M and Chess, J},
abstractNote = {We report on the use of a 5.8 GHz microwave applicator to treat choroidal melanoma (Greene) in rabbits. The physical requirements needed to treat these intraocular tumors are quite different from those encountered elsewhere in the body. From a trans-scleral approach the penetration needed is minimal (5 to 10 mm.). The fibrous sclera is the only structure between the heat source and the tumor. The sclera has a relatively low water content when compared to tumor. This fact in addition to the frequency dependent interactions of tissue and electromagnetic radiation, results in an advantage to the use of the 5.8 GHz microwave device in treating intraocular malignancies.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1983},
month = {1}
}

Conference:
Other availability
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