Radionuclide administration to nursing mothers: mathematically derived guidelines

Journal Article · Fri Aug 01 00:00:00 EDT 1986 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.160.2.3726137· OSTI ID:5118473

Romney, B M; Nickoloff, E L; Esser, P D; Alderson, P O

We determined a formula to establish objective guidelines for the administration of radionuclides to nursing mothers. The formula is based on the maximum permissible dose to the infant's critical organ, serial measurements of breast milk activity, milk volume, and dose to the critical organ per microcurie in milk. Using worst-case assumptions, we believe that cessation of nursing for 24 hours after administration of technetium labeled radiopharmaceuticals is sufficient for safety. Longer-lived agents require greater delays. Iodine-123 radiopharmaceuticals are preferable to iodine-131 agents and should always be used when studying the unblocked thyroid.

• OSTI ID: 5118473
• Journal Information: Radiology; (United States), Vol. 2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
RADIONUCLIDE ADMINISTRATION
WOMEN
INFANTS
IODINE 123
IODINE 131
LACTATION
MILK
PREGNANCY
RADIATION DOSES
RADIOPHARMACEUTICALS
RECOMMENDATIONS
TECHNETIUM 99
AGE GROUPS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY FLUIDS
CHILDREN
DAYS LIVING RADIOISOTOPES
DOSES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
FEMALES
FOOD
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MAMMALS
MAN
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
PRIMATES
RADIOISOTOPES
TECHNETIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560161* - Radionuclide Effects
Kinetics
& Toxicology- Man
550601 - Medicine- Unsealed Radionuclides in Diagnostics