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Title: Reduced tar, nicotine, and carbon monoxide exposure while smoking ultralow- but not low-yield cigarettes

Journal Article · · JAMA, J. Am. Med. Assoc.; (United States)

An unresolved public health issue is whether some modern cigarettes are less hazardous than other and whether patients who cannot stop smoking should be advised to switch to lower-yield cigarettes. The authors studied tar (estimated by urine mutagenicity), nicotine, and carbon monoxide exposure in habitual smokers switched from their usual brand to high- (15 mg of tar), low- (5 mg of tar), or ultralow-yield (1 mg of tar) cigarettes. There were no differences in exposure comparing high- or low-yield cigarettes, but tar and nicotine exposures were reduced by 49% and 56%, respectively, and carbon monoxide exposure by 36% while smoking ultralow-yield cigarettes. Similarly, in 248 subjects smoking their self-selected brand, nicotine intake, estimated by blood concentrations of its metabolite continine, was 40% lower in those who smoked ultralow but no different in those smoking higher yields of cigarettes. The data indicate that ultralow-yield cigarettes do deliver substantial doses of tar, nicotine, and carbon monoxide, but that exposure are considerably less than for other cigarettes.

Research Organization:
San Francisco General Hospital Medical Center, CA
OSTI ID:
5070819
Journal Information:
JAMA, J. Am. Med. Assoc.; (United States), Vol. 256:2
Country of Publication:
United States
Language:
English

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