Exposure to naphthalene-diisocyanate in a rubber plant: symptoms and lung function
Twenty-three subjects exposed to naphthalene-diisocyanate (NDI, (mean air concentration 0.002-0.007 mg/m/sup 3/)) were examined with regard to symptoms and pulmonary function. Irritation of the eyes, cough, and exertion dyspnea were more common in exposed subjects than in unexposed controls. Closing volume, as a percentage of vital capacity (CV%), was 6% higher than the reference value on Monday morning after 2 days with no exposure to NDI. The other lung function variables were normal. Two days of industrial exposure caused no further change in any lung function variable. The difference between measured and expected CV% increased with age in the exposed subjects. Five employees who had complained of severe symptoms during NDI exposure and who, therefore, had been transferred to other tasks with no exposure to NDI, displayed marked increases in CV% and a reduction in the forced vital capacity by an average of 0.61. Smokers and nonsmokers displayed similar lung function changes.
- Research Organization:
- Karolinska Hospital, Stockholm, Sweden
- OSTI ID:
- 5070783
- Journal Information:
- Arch. Environ. Health; (United States), Vol. 41:2
- Country of Publication:
- United States
- Language:
- English
Similar Records
Exposure, lung function, and symptoms in car painters exposed to hexamethylendiisocyanate and biuret modified hexamethylendiisocyanate
Health effects of air pollution due to coal combustion in the Chestnut Ridge Region of Pennsylvania: results of cross-sectional analysis in adults
Related Subjects
ISOCYANATES
HEALTH HAZARDS
LUNGS
BIOLOGICAL FUNCTIONS
INJURIES
NAPHTHALENE
AIR POLLUTION
EXPERIMENTAL DATA
OCCUPATIONAL EXPOSURE
RUBBER INDUSTRY
SYMPTOMS
AROMATICS
BODY
CONDENSED AROMATICS
DATA
FUNCTIONS
HAZARDS
HYDROCARBONS
INDUSTRY
INFORMATION
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANS
POLLUTION
RESPIRATORY SYSTEM
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)