Nasopharyngeal cancer: a review of 1605 patients treated radically with cobalt 60. [5- and 10-year survival rates and complications of radiotherapy]
A retrospective study was performed on 1605 patients with histologically proven and radically treated nasopharyngeal carcinoma. All were followed for a minimum of five years; 833 patients had a minimum follow-up period of ten years. Treatment results were reviewed according to: (1) size of primary tumor; (2) base of skull invasion; (3) cranial nerve involvement; (4) cervical node metastases; and (5) distant spread. An appropriate staging system was developed that reflected these prognostic factors. The evidence presented indicates that in this series of patients, base of skull involvement was less ominous than cranial nerve involvement. Unilteral lymph node involvement carried a better prognosis than bilateral neck nodes, this was the poorest sign of all since it predicted distant metastases. The average 5-year survival rate for 1605 patients in all stages, was 529/1605(32.1%); the 10-year survival rate for 833 patients in all stages was 20.2%.
- Research Organization:
- National Taiwan Univ., Taipei
- OSTI ID:
- 5060001
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 6:4
- Country of Publication:
- United States
- Language:
- English
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RADIOINDUCTION
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DELAYED RADIATION EFFECTS
MYELITIS
NERVES
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SPINAL CORD
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COBALT
FRACTIONATED IRRADIATION
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DIGESTIVE SYSTEM
DISEASES
ELECTROMAGNETIC RADIATION
ELEMENTS
EXTERNAL IRRADIATION
INJURIES
IONIZING RADIATIONS
IRRADIATION
LOCAL RADIATION EFFECTS
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NECROSIS
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PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATION INJURIES
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SKELETAL DISEASES
SKELETON
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