Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]

Paloyan, E; Lawrence, A M

doi:10.1001/archderm.1978.01640130017004

Title: Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]

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Abstract

There is a potential hazard of thyroid cancer after exposure to external irradiation for the treatment of adolescent acne vulgaris. We noted a 60% incidence of thyroid carcinoma among 20 patients with such a history, who were operated on for thyroid nodules during a five-year period. Eighty-three percent of the patients with carcinoma had either a follicular or a mixed papillary-follicular carcinoma; 17% had a papillary carcinoma; 33% had regional node metastases; none had evidence of distant metastases. The interval between radiation exposure and thyroidectomy ranged from nine to 41 years. This association of thyroid neoplasms and a prior history of radiation for acne vulgaris may be coincidental and therefore remains to be proved by retrospective surveys of large numbers of treated patients with appropriate controls.

Authors:: Paloyan, E; Lawrence, A M

Publication Date:: Sun Jan 01 00:00:00 EST 1978

Research Org.:: Loyola Univ. Stritch School of Medicine, Hines, IL

OSTI Identifier:: 5038381

Resource Type:: Journal Article

Journal Name:: Arch. Dermatol.; (United States)

Additional Journal Information:: Journal Volume: 114:1

Country of Publication:: United States

Language:: English

Subject:: 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; NEOPLASMS; RADIOINDUCTION; RADIOTHERAPY; SIDE EFFECTS; THYROID; BIOLOGICAL RADIATION EFFECTS; HEALTH HAZARDS; METASTASES; PATIENTS; SKIN DISEASES; X RADIATION; BIOLOGICAL EFFECTS; BODY; DISEASES; ELECTROMAGNETIC RADIATION; ENDOCRINE GLANDS; GLANDS; HAZARDS; IONIZING RADIATIONS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOLOGY; THERAPY; 560151* - Radiation Effects on Animals- Man

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                    Paloyan, E, and Lawrence, A M. Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation].  United States: N. p., 1978. 
        Web.  doi:10.1001/archderm.1978.01640130017004.

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                    Paloyan, E, & Lawrence, A M. Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation].  United States.  https://doi.org/10.1001/archderm.1978.01640130017004

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                    Paloyan, E, and Lawrence, A M. 1978.  
        "Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]".  United States.  https://doi.org/10.1001/archderm.1978.01640130017004.

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@article{osti_5038381,

  title        = {Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]},

  author       = {Paloyan, E and Lawrence, A M},

  abstractNote = {There is a potential hazard of thyroid cancer after exposure to external irradiation for the treatment of adolescent acne vulgaris. We noted a 60% incidence of thyroid carcinoma among 20 patients with such a history, who were operated on for thyroid nodules during a five-year period. Eighty-three percent of the patients with carcinoma had either a follicular or a mixed papillary-follicular carcinoma; 17% had a papillary carcinoma; 33% had regional node metastases; none had evidence of distant metastases. The interval between radiation exposure and thyroidectomy ranged from nine to 41 years. This association of thyroid neoplasms and a prior history of radiation for acne vulgaris may be coincidental and therefore remains to be proved by retrospective surveys of large numbers of treated patients with appropriate controls.},

  doi          = {10.1001/archderm.1978.01640130017004},

  url          = {https://www.osti.gov/biblio/5038381},
  journal      = {Arch. Dermatol.; (United States)},
number       = ,

  volume       = 114:1,

  place        = {United States},

  year         = {Sun Jan 01 00:00:00 EST 1978},

  month        = {Sun Jan 01 00:00:00 EST 1978}

}

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