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Title: Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]

Abstract

There is a potential hazard of thyroid cancer after exposure to external irradiation for the treatment of adolescent acne vulgaris. We noted a 60% incidence of thyroid carcinoma among 20 patients with such a history, who were operated on for thyroid nodules during a five-year period. Eighty-three percent of the patients with carcinoma had either a follicular or a mixed papillary-follicular carcinoma; 17% had a papillary carcinoma; 33% had regional node metastases; none had evidence of distant metastases. The interval between radiation exposure and thyroidectomy ranged from nine to 41 years. This association of thyroid neoplasms and a prior history of radiation for acne vulgaris may be coincidental and therefore remains to be proved by retrospective surveys of large numbers of treated patients with appropriate controls.

Authors:
;
Publication Date:
Research Org.:
Loyola Univ. Stritch School of Medicine, Hines, IL
OSTI Identifier:
5038381
Resource Type:
Journal Article
Journal Name:
Arch. Dermatol.; (United States)
Additional Journal Information:
Journal Volume: 114:1
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; NEOPLASMS; RADIOINDUCTION; RADIOTHERAPY; SIDE EFFECTS; THYROID; BIOLOGICAL RADIATION EFFECTS; HEALTH HAZARDS; METASTASES; PATIENTS; SKIN DISEASES; X RADIATION; BIOLOGICAL EFFECTS; BODY; DISEASES; ELECTROMAGNETIC RADIATION; ENDOCRINE GLANDS; GLANDS; HAZARDS; IONIZING RADIATIONS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOLOGY; THERAPY; 560151* - Radiation Effects on Animals- Man

Citation Formats

Paloyan, E., and Lawrence, A.M. Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]. United States: N. p., 1978. Web. doi:10.1001/archderm.1978.01640130017004.
Paloyan, E., & Lawrence, A.M. Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]. United States. doi:10.1001/archderm.1978.01640130017004.
Paloyan, E., and Lawrence, A.M. Sun . "Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]". United States. doi:10.1001/archderm.1978.01640130017004.
@article{osti_5038381,
title = {Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]},
author = {Paloyan, E. and Lawrence, A.M.},
abstractNote = {There is a potential hazard of thyroid cancer after exposure to external irradiation for the treatment of adolescent acne vulgaris. We noted a 60% incidence of thyroid carcinoma among 20 patients with such a history, who were operated on for thyroid nodules during a five-year period. Eighty-three percent of the patients with carcinoma had either a follicular or a mixed papillary-follicular carcinoma; 17% had a papillary carcinoma; 33% had regional node metastases; none had evidence of distant metastases. The interval between radiation exposure and thyroidectomy ranged from nine to 41 years. This association of thyroid neoplasms and a prior history of radiation for acne vulgaris may be coincidental and therefore remains to be proved by retrospective surveys of large numbers of treated patients with appropriate controls.},
doi = {10.1001/archderm.1978.01640130017004},
journal = {Arch. Dermatol.; (United States)},
number = ,
volume = 114:1,
place = {United States},
year = {1978},
month = {1}
}