An overview of interstitial brachytherapy and hyperthermia
Interstitial thermoradiotherapy, an experimental cancer treatment that combines interstitial radiation implants (brachytherapy) and interstitial hyperthermia, is in the early stages of investigation. In accordance with the procedure used in a current national trial protocol, a 60-minute hyperthermia treatment is administered after catheters are placed into the tumor area while the patient is under general anesthesia. This is immediately followed by loading of radioactive Iridium-192 seeds into the catheters for a defined period of time. Once the prescribed radiation dose is delivered, the radioactive sources are removed and a second, 60-minute hyperthermia treatment is administered. Clinical trials with hyperthermia in combination with radiation have increased in recent years. Nurses caring for these patients need to become more knowledgeable about this investigational therapy. This paper provides an overview of the biologic rationale for this therapy, as well as a description of the delivery method and clinical application. Specific related nursing interventions are defined in a nursing protocol.23 references.
- OSTI ID:
- 5027137
- Journal Information:
- Oncology Nursing Forum; (USA), Vol. 16:6; ISSN 0190-535X
- Country of Publication:
- United States
- Language:
- English
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HYPERTHERMIA
RADIOSENSITIVITY EFFECTS
NEOPLASMS
RADIOTHERAPY
IRIDIUM 192
PATIENTS
PLANNING
RADIATION SOURCE IMPLANTS
REVIEWS
SYNERGISM
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY TEMPERATURE
DAYS LIVING RADIOISOTOPES
DISEASES
DOCUMENT TYPES
ELECTRON CAPTURE RADIOISOTOPES
HEAVY NUCLEI
IMPLANTS
INTERNAL CONVERSION RADIOISOTOPES
IRIDIUM ISOTOPES
ISOMERIC TRANSITION
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)