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Title: New imaging systems in nuclear medicine. Final report, January 1, 1993--December 31, 1995

Abstract

The aim of this program has been to improve the performance of positron emission tomography (PET) to achieve high resolution with high sensitivity. Towards this aim, the authors have carried out the following studies: (1) explored new techniques for detection of annihilation radiation including new detector materials and system geometries, specific areas that they have studied include--exploration of factors related to resolution and sensitivity of PET instrumentation including geometry, detection materials and coding, and the exploration of technique to improve the image quality by use of depth of interaction and increased sampling; (2) complete much of the final testing of PCR-II, an analog-coded cylindrical positron tomograph, developed and constructed during the current funding period; (3) developed the design of a positron microtomograph with mm resolution for quantitative studies in small animals, a single slice version of this device has been designed and studied by use of computer simulation; (4) continued and expanded the program of biological studies in animal models. Current studies have included imaging of animal models of Parkinson`s and Huntington`s disease and cancer. These studies have included new radiopharmaceuticals and techniques involving molecular biology.

Publication Date:
Research Org.:
Massachusetts General Hospital, Boston, MA (United States)
Sponsoring Org.:
USDOE Office of Energy Research, Washington, DC (United States)
OSTI Identifier:
491518
Report Number(s):
DOE/ER/60519-T5
ON: DE97006656; TRN: 97:012492
DOE Contract Number:  
FG02-87ER60519
Resource Type:
Technical Report
Resource Relation:
Other Information: PBD: [1995]
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; POSITRON COMPUTED TOMOGRAPHY; PROGRESS REPORT; NUCLEAR MEDICINE; PERFORMANCE; OPTIMIZATION; IMAGE PROCESSING; SPATIAL RESOLUTION; BIOLOGICAL MODELS; PHANTOMS; RADIOPHARMACEUTICALS

Citation Formats

. New imaging systems in nuclear medicine. Final report, January 1, 1993--December 31, 1995. United States: N. p., 1995. Web. doi:10.2172/491518.
. New imaging systems in nuclear medicine. Final report, January 1, 1993--December 31, 1995. United States. https://doi.org/10.2172/491518
. 1995. "New imaging systems in nuclear medicine. Final report, January 1, 1993--December 31, 1995". United States. https://doi.org/10.2172/491518. https://www.osti.gov/servlets/purl/491518.
@article{osti_491518,
title = {New imaging systems in nuclear medicine. Final report, January 1, 1993--December 31, 1995},
author = {},
abstractNote = {The aim of this program has been to improve the performance of positron emission tomography (PET) to achieve high resolution with high sensitivity. Towards this aim, the authors have carried out the following studies: (1) explored new techniques for detection of annihilation radiation including new detector materials and system geometries, specific areas that they have studied include--exploration of factors related to resolution and sensitivity of PET instrumentation including geometry, detection materials and coding, and the exploration of technique to improve the image quality by use of depth of interaction and increased sampling; (2) complete much of the final testing of PCR-II, an analog-coded cylindrical positron tomograph, developed and constructed during the current funding period; (3) developed the design of a positron microtomograph with mm resolution for quantitative studies in small animals, a single slice version of this device has been designed and studied by use of computer simulation; (4) continued and expanded the program of biological studies in animal models. Current studies have included imaging of animal models of Parkinson`s and Huntington`s disease and cancer. These studies have included new radiopharmaceuticals and techniques involving molecular biology.},
doi = {10.2172/491518},
url = {https://www.osti.gov/biblio/491518}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Sun Dec 31 00:00:00 EST 1995},
month = {Sun Dec 31 00:00:00 EST 1995}
}