Assignment of the human and mouse genes for muscle ecto mono (ADPribosyl)transferase to a conserved linkage group on human chromosome 11p15 and mouse chromosome 7

Journal Article · Thu Aug 15 00:00:00 EDT 1996 · Genomics

DOI:https://doi.org/10.1006/geno.1996.0451· OSTI ID:484351

Koch-Nolte, F; Kuehl, M; Haag, F ^[1]

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1. Univ. Hospital, Hamburg (Germany); and others

This report describes the localization of the human and mouse genes for muscle ecto mono (ADProbosyl)transferase to human chromosome 11p15 and mouse chromosome 7 using polymerase chain reaction of somatic cell hybrids. Mono ADP-ribosylation is the mechanism by which bacterial toxins interfere with protein biosynthesis in human host cells. 11 refs., 1 fig.

• OSTI ID: 484351
• Journal Information: Genomics, Vol. 36, Issue 1; Other Information: PBD: 15 Aug 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
56 BIOLOGY AND MEDICINE
APPLIED STUDIES
TRANSFERASES
GENETIC MAPPING
DNA SEQUENCING
HUMAN CHROMOSOMES
BIOLOGICAL EVOLUTION
TOXINS
BIOLOGICAL EFFECTS
PROTEINS
BIOSYNTHESIS
MICE
POLYMERASE CHAIN REACTION
HYBRIDIZATION
SOMATIC CELLS
GENE RECOMBINATION
BIOLOGICAL MARKERS