Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization

Journal Article · Thu Aug 15 00:00:00 EDT 1996 · Genomics

DOI:https://doi.org/10.1006/geno.1996.0448· OSTI ID:484348

Furuta, Hiroto; Le Beau, M M; Fernald, A A ^[1]

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1. Univ. of Chicago, IL (United States); and others

Complementary DNA clones encoding human hexokinase III were isolated from a liver cDNA library. There was 84.7% identity between the amino acid sequences of human and rat hexokinase III. RNA blotting showed the presence of hexokinase III mRNA in liver and lung. Fluorescence in situ hybridization localized the human hexokinase III gene (HK3) to chromosome 5, band q35.2. 11 refs., 3 figs.

• OSTI ID: 484348
• Journal Information: Genomics, Vol. 36, Issue 1; Other Information: PBD: 15 Aug 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
HUMAN CHROMOSOME 5
GENETIC MAPPING
HEXOKINASE
TISSUE DISTRIBUTION
DNA SEQUENCING
GENE REGULATION
DNA-CLONING
ENZYME ACTIVITY
GLUCOSE
PHOSPHORYLATION
METABOLISM
MAN
DIABETES MELLITUS
HEREDITARY DISEASES
DNA HYBRIDIZATION
FLUORESCENCE
RATS
LIVER
LUNGS
AMINO ACID SEQUENCE