POSTIRRADIATION TREATMENT OF LETHAL TOTAL BODY IRRADIATION BY CELL-FREE SPLEEN EXTRACTS

Journal Article · Thu Mar 01 00:00:00 EST 1962 · Am. J. Roentgenol., Radium Therapy Nuclear Med.

OSTI ID:4811493

Ellinger, F

Post-irradiation treatment with homologous as well as heterologous cell- free spleen extracts in appropriate doses was found to reduce radiation mortality in guinea pigs. Treatment with cell-free spleen extracts restored spleen and bone marrow. Other advantages of the use of spleen extracts over marrow grafts are also given along with its advantages over chemicals. Spleen extract treatment can be started after irradiation (during the latent period) when most chemicals fail to reduce mortality. Treatment with cell-free spleen extracts is also free from unpleasant side and deleterious late effects. (P.C.H.)

• Research Organization: Naval Medical Research Inst., Bethesda, Md.
• NSA Number: NSA-16-009924
• OSTI ID: 4811493
• Journal Information: Am. J. Roentgenol., Radium Therapy Nuclear Med., Vol. Vol: 87; Other Information: Orig. Receipt Date: 31-DEC-62
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BONE MARROW
CHEMICALS
GUINEA PIGS
LIFETIME
RADIATION EFFECTS
RADIATION SICKNESS
RECOVERY
SPLEEN
THERAPY
TISSUE EXTRACTS
TISSUES