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Title: CHROMOSOMES OF TWO CASES OF HUMAN CHRONIC MYELOID LEUKAEMIA

Abstract

The presence of an abnormally small chromosome (Ph/sup 1) replacing one of the smallest acrocentric autosomes is looked for in blood cells of two patients with chronic myeloid leukemia. The Ph/sup 1/ is observed in about half the cells of one of the patients, who has received no treatment for the disease. No Ph/sup 1/ is found in the cells of the other pa tient, who has a long history of diagnostic irradiations (about 180 r) and an unusually slow progression of the disease. The role of the Ph/sup 1/ chromosome in the neoplastic process is discussed. (T.F.H.)

Authors:
Publication Date:
Research Org.:
Wakari Hospital, Dunedin, N.Z.
Sponsoring Org.:
USDOE
OSTI Identifier:
4789874
NSA Number:
NSA-16-017366
Resource Type:
Journal Article
Journal Name:
Nature
Additional Journal Information:
Journal Volume: Vol: 194; Other Information: Orig. Receipt Date: 31-DEC-62
Country of Publication:
Country unknown/Code not available
Language:
English
Subject:
BIOLOGY AND MEDICINE

Citation Formats

Fitzgerald, P.H. CHROMOSOMES OF TWO CASES OF HUMAN CHRONIC MYELOID LEUKAEMIA. Country unknown/Code not available: N. p., 1962. Web. doi:10.1038/194393a0.
Fitzgerald, P.H. CHROMOSOMES OF TWO CASES OF HUMAN CHRONIC MYELOID LEUKAEMIA. Country unknown/Code not available. doi:10.1038/194393a0.
Fitzgerald, P.H. Sat . "CHROMOSOMES OF TWO CASES OF HUMAN CHRONIC MYELOID LEUKAEMIA". Country unknown/Code not available. doi:10.1038/194393a0.
@article{osti_4789874,
title = {CHROMOSOMES OF TWO CASES OF HUMAN CHRONIC MYELOID LEUKAEMIA},
author = {Fitzgerald, P.H.},
abstractNote = {The presence of an abnormally small chromosome (Ph/sup 1) replacing one of the smallest acrocentric autosomes is looked for in blood cells of two patients with chronic myeloid leukemia. The Ph/sup 1/ is observed in about half the cells of one of the patients, who has received no treatment for the disease. No Ph/sup 1/ is found in the cells of the other pa tient, who has a long history of diagnostic irradiations (about 180 r) and an unusually slow progression of the disease. The role of the Ph/sup 1/ chromosome in the neoplastic process is discussed. (T.F.H.)},
doi = {10.1038/194393a0},
journal = {Nature},
number = ,
volume = Vol: 194,
place = {Country unknown/Code not available},
year = {1962},
month = {4}
}