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Title: A 39-year follow-up of the U.K. oil refinery and distribution center studies: Results for kidney cancer and leukemia

Abstract

This paper presents briefly some of the principal results of a mortality analysis of a cohort of workers employed for at least 1 year between 1950 and 1975 at eight oil refineries and approximately 750 distribution centers in the U.K, together with detailed results for kidney cancer and leukemia. Over 99% of the workers were successfully traced. Their mortality was compared with that of all males in the national population. The mortality from all causes of death is lower than that of the comparison population in both studies, and reduced mortality is also found for many of the major nonmalignant causes of death. In the refinery study, some increased mortality patterns are found for diseases of the arteries, and no healthy worker effect is found in the distribution center study for ischemic heart disease. Mortality from all neoplasms is lower than expected overall in both studies, largely due to a deficit of deaths from malignant neoplasm of the lung. Mortality from malignant neoplasm of the kidney is increased overall in the distribution center study, and in drivers in particular. The mortality from this disease increases with increased time since first exposure. The observed deaths from leukemia are slightly less thanmore » expected in the refinery study and slightly more than expected in the distribution center study. One refinery shows increased mortality due to in myeloid leukemia, and mortality is increased among refinery operators. Mortality is also raised in distribution center drivers, particularly for myeloid leukemias, including acute myeloid leukemia. 71 refs., 9 tabs.« less

Authors:
 [1]
  1. Thames Polytechnic, London (United Kingdom)
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
478937
Report Number(s):
CONF-9111356-
Journal ID: EVHPAZ; ISSN 0091-6765; TRN: 97:000657-0011
Resource Type:
Journal Article
Journal Name:
Environmental Health Perspectives
Additional Journal Information:
Journal Volume: 101; Journal Issue: Suppl.6; Conference: International symposium on the health effects of gasoline, Miami, FL (United States), 5-8 Nov 1991; Other Information: PBD: Dec 1993
Country of Publication:
United States
Language:
English
Subject:
02 PETROLEUM; GASOLINE; HEALTH HAZARDS; MYELOID LEUKEMIA; RISK ASSESSMENT; KIDNEYS; NEOPLASMS; OCCUPATIONAL EXPOSURE; PETROLEUM REFINERIES; MORTALITY; EPIDEMIOLOGY; STATISTICAL DATA; OCCUPATIONAL DISEASES

Citation Formats

Rushton, L. A 39-year follow-up of the U.K. oil refinery and distribution center studies: Results for kidney cancer and leukemia. United States: N. p., 1993. Web. doi:10.1289/ehp.93101s677.
Rushton, L. A 39-year follow-up of the U.K. oil refinery and distribution center studies: Results for kidney cancer and leukemia. United States. https://doi.org/10.1289/ehp.93101s677
Rushton, L. 1993. "A 39-year follow-up of the U.K. oil refinery and distribution center studies: Results for kidney cancer and leukemia". United States. https://doi.org/10.1289/ehp.93101s677.
@article{osti_478937,
title = {A 39-year follow-up of the U.K. oil refinery and distribution center studies: Results for kidney cancer and leukemia},
author = {Rushton, L},
abstractNote = {This paper presents briefly some of the principal results of a mortality analysis of a cohort of workers employed for at least 1 year between 1950 and 1975 at eight oil refineries and approximately 750 distribution centers in the U.K, together with detailed results for kidney cancer and leukemia. Over 99% of the workers were successfully traced. Their mortality was compared with that of all males in the national population. The mortality from all causes of death is lower than that of the comparison population in both studies, and reduced mortality is also found for many of the major nonmalignant causes of death. In the refinery study, some increased mortality patterns are found for diseases of the arteries, and no healthy worker effect is found in the distribution center study for ischemic heart disease. Mortality from all neoplasms is lower than expected overall in both studies, largely due to a deficit of deaths from malignant neoplasm of the lung. Mortality from malignant neoplasm of the kidney is increased overall in the distribution center study, and in drivers in particular. The mortality from this disease increases with increased time since first exposure. The observed deaths from leukemia are slightly less than expected in the refinery study and slightly more than expected in the distribution center study. One refinery shows increased mortality due to in myeloid leukemia, and mortality is increased among refinery operators. Mortality is also raised in distribution center drivers, particularly for myeloid leukemias, including acute myeloid leukemia. 71 refs., 9 tabs.},
doi = {10.1289/ehp.93101s677},
url = {https://www.osti.gov/biblio/478937}, journal = {Environmental Health Perspectives},
number = Suppl.6,
volume = 101,
place = {United States},
year = {Wed Dec 01 00:00:00 EST 1993},
month = {Wed Dec 01 00:00:00 EST 1993}
}