PATHOLOGICAL EFFECTS OF THYROID IRRADIATION. A report of a Panel of Experts from the Committees on the Biological Effects of Atomic Radiation National Academy of Sciences-National Research council

Technical Report · 01 July 1962

OSTI ID:4771266

Therapeutic doses of x rays to the thyroid region of children have beem followed after some years by the development of thyroid cancer in a very small proportion of cases. The tumor incidence is not demonstrably dose dependent, but it exceeds that found in unirradiated children. X rays are more effective than iodine-131 in producing thyroid cancer, for equal energies delivered to the gland. The induction of thyroid tumor appears to be enhanced by the irradiation of tissues, as yet unidemtifled, im additiom to the thyroid itself. At high dose levels the thyroids of infants and childrem may be somewhat more susceptible to radiation carcinogenesis than those of adults. Evidence on this point is lacking at very low doses because no cases of thyromd cancer at these levels is kmowm. Radioactive iodime has been shown to be carcinogenic in some animals, but no case of thyroid cancer ascribable to it has been found in man. (auth)

• Research Organization: Federal Radiation Council, Washington, D.C.
• DOE Contract Number: NONE
• NSA Number: NSA-16-030210
• OSTI ID: 4771266
• Report Number(s): NP-12021
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
CARCINOGENESIS
ENERGY LEVELS
IODINE 131
MAN
MEDICINE
QUANTITY RATIO
RADIATION DOSES
RADIOSENSITIVITY
RADIOTHERAPY
THYROID
TUMORS
X RADIATION