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Title: The Value of Grenz-Ray Therapy for Acne Vulgaris

Abstract

In view of recent efforts to eliminate the use of radiotherapy for benign conditions or conditions treatable by other means, to avoid the possible detrimental effects of radiation, an evaluation of this treatment of acne was made. In a controlled, double-blind study in 40 patients, one area of skin received 1800 r (in thrice weekly 100-r doses) of 10-kv x irradiation. Comparable areas of skin were shamirradiated with the x-ray apparatus shielded by lead. In no case had the acne cleared up on the irradiated side. ln about half of the cases no difference was seen between the two areas. The remaining showed a systematic difference in favor of the treated side 2-6 weeks after treatment. However, in the majority of cases no improvement attributable to grenz-ray irradiation could be ascertained. It is concluded that grenz-ray therapy of acne, at least at the dosage used, is ineffective. At these doses, inhibition of sebaceous gland secretion would not be expected to occur. Severe erythema followed by peeling was not seen in these patients.

Authors:
; ; ;
Publication Date:
Research Org.:
Univ. of Amsterdam
Sponsoring Org.:
USDOE
OSTI Identifier:
4660763
NSA Number:
NSA-17-035364
Resource Type:
Journal Article
Journal Name:
Dermatology
Additional Journal Information:
Journal Volume: 126; Journal Issue: 5; Other Information: Orig. Receipt Date: 31-DEC-63; Journal ID: ISSN 1018-8665
Country of Publication:
Country unknown/Code not available
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACNE; GLANDS; INSTRUMENTS; LEAD; MAN; RADIATION DOSES; RADIOTHERAPY; SEBACEOUS GLANDS; SHIELDING; SKIN; X RADIATION

Citation Formats

de Groot, W. P., Prakken, J. R., Verbeek, Ann M. J. A., and Woerdeman, M. J. The Value of Grenz-Ray Therapy for Acne Vulgaris. Country unknown/Code not available: N. p., 1963. Web. doi:10.1159/000254933.
de Groot, W. P., Prakken, J. R., Verbeek, Ann M. J. A., & Woerdeman, M. J. The Value of Grenz-Ray Therapy for Acne Vulgaris. Country unknown/Code not available. doi:10.1159/000254933.
de Groot, W. P., Prakken, J. R., Verbeek, Ann M. J. A., and Woerdeman, M. J. Tue . "The Value of Grenz-Ray Therapy for Acne Vulgaris". Country unknown/Code not available. doi:10.1159/000254933.
@article{osti_4660763,
title = {The Value of Grenz-Ray Therapy for Acne Vulgaris},
author = {de Groot, W. P. and Prakken, J. R. and Verbeek, Ann M. J. A. and Woerdeman, M. J.},
abstractNote = {In view of recent efforts to eliminate the use of radiotherapy for benign conditions or conditions treatable by other means, to avoid the possible detrimental effects of radiation, an evaluation of this treatment of acne was made. In a controlled, double-blind study in 40 patients, one area of skin received 1800 r (in thrice weekly 100-r doses) of 10-kv x irradiation. Comparable areas of skin were shamirradiated with the x-ray apparatus shielded by lead. In no case had the acne cleared up on the irradiated side. ln about half of the cases no difference was seen between the two areas. The remaining showed a systematic difference in favor of the treated side 2-6 weeks after treatment. However, in the majority of cases no improvement attributable to grenz-ray irradiation could be ascertained. It is concluded that grenz-ray therapy of acne, at least at the dosage used, is ineffective. At these doses, inhibition of sebaceous gland secretion would not be expected to occur. Severe erythema followed by peeling was not seen in these patients.},
doi = {10.1159/000254933},
journal = {Dermatology},
issn = {1018-8665},
number = 5,
volume = 126,
place = {Country unknown/Code not available},
year = {1963},
month = {1}
}