Assignment of the human PP5/TFPI-2 gene to 7q22 by FISH and PCR-based human/rodent cell hybrid mapping panel analysis

Journal Article · Mon Jul 01 00:00:00 EDT 1996 · Genomics

DOI:https://doi.org/10.1006/geno.1996.0353· OSTI ID:466049

Miyagi, Yohei; Aoki, Ichiro; Misugi, Kazuaki ^[1]

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1. Yokohama City Univ. School of Medicine, Kanazawa-ku (Japan); and others

This report describes the localization of the human placental protein 5 (PP5)/tissue factor pathway inhibitor (TFPI)-2 gene to human chromosome 7q22 using fluorescence in situ hybridization and polymerase chain reaction of human/rodent cell hybrids. The relationship of PP5/TFPI-2 gene mutations to malignant tumors is suggested. 13 refs., 1 fig.

• OSTI ID: 466049
• Journal Information: Genomics, Vol. 35, Issue 1; Other Information: PBD: 1 Jul 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
GENES
DNA-CLONING
GENETIC MAPPING
DNA SEQUENCING
STRUCTURE-ACTIVITY RELATIONSHIPS
TISSUE DISTRIBUTION
GENE MUTATIONS
HUMAN CHROMOSOME 7
CHROMOSOMAL ABERRATIONS
MAN
HEREDITARY DISEASES
CARCINOMAS
NEOPLASMS
PROTEINS
FLUORESCENCE
IN-SITU HYBRIDIZATION
AMINO ACID SEQUENCE