PET camera designs for imaging breast cancer and axillary node involvement
- Lawrence Berkeley Laboratory, CA (United States); and others
We propose a design for a PET camera dedicated to imaging breast tumors with high selectivity and specificity, but low cost and injected FDG dose. This extends a previous design by providing higher sensitivity and more accurate images by (1) completing the detector {open_quotes}ring{close_quotes} around the breast, which increases the sensitivity by a factor of two and improves angular sampling for the tomographic reconstruction, and (2) constructing the detector ring with modules having better depth of interaction measurement resolution, which reduces the extreme parallax errors present when the object to be imaged is adjacent to the detectors. A similar design can image the auxillary nodes and determine the extent of nodal involvement. The critical requirements are that a septaless, complete detector ring encircle the shoulder region and that the detector modules have good depth of interaction measurements resolution. This geometry has nearly 100-fold greater sensitivity than a conventional 2-D PET camera-a factor of 4-5 due to increased solid angle and a factor of 20 from lower attenuation. The critical element is the detector module, which is an 8x8 array of 3 mm square by 25 mm deep LSO (Lu{sub 2}SiO{sub 5}:Ce) scintillator crystals coupled on one end to a common photomultiplier tube (PMT) and on the opposite end to a silicon photodiode (PD) array. The PMT provides a timing pulse and energy discrimination for the 64 crystals in the module and the PDs identify the crystal of interaction. Each LSO crystal is coated with a {open_quotes}lossy{close_quotes} reflector, so the ratio of light detected in the PD and PMT can be used to measure the position of interaction with 5 mm fwhm accuracy. Thirty such modules can be arranged to form either a breast camera or an auxillary node camera, and existing tomographic data acquisition hardware and reconstruction algorithms can easily be adapted to accumulate and reconstruct data from this configuration.
- DOE Contract Number:
- AC03-76SF00098
- OSTI ID:
- 441588
- Report Number(s):
- CONF-950603-; ISSN 0161-5505; CNN: Grant P01 25840; Grant R01 NS29655; TRN: 96:002093-0013
- Journal Information:
- Journal of Nuclear Medicine, Vol. 36, Issue Suppl.5; Conference: 42. annual meeting of the Society of Nuclear Medicine, Minneapolis, MN (United States), 12-15 Jun 1995; Other Information: PBD: May 1995
- Country of Publication:
- United States
- Language:
- English
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