Comparison of technetium-99m-HMPAO and technetium-99m-ECD cerebral SPECT images in Alzheimer`s disease

Journal Article · Fri Nov 01 00:00:00 EST 1996 · Journal of Nuclear Medicine

OSTI ID:433040

Dyck, C.H. van; Lin, C H; Smith, E O ^[1]

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1. Yale Univ. School of Medicine, New Haven, CT (United States); and others

SPECT has shown increasing promise as a diagnostic tool in Alzheimer`s disease (AD). Recently, a new SPECT brain perfusion agent, {sup 99m}Tc-ethyl cysteinate dimer ({sup 99m}Tc-ECD) has emerged with purported advantages in image quality over the established tracer, {sup 99m}Tc-hexamethylpropyleneamine oxime ({sup 99m}Tc-HMPAO). This research aimed to compare cerebral images for ({sup 99m}Tc-HMPAO). This research aimed to compare cerebral images for {sup 99}mTc-HMPAO and {sup 99m}Tc-ECD in discriminating patients with AD form control subjects. 51 refs., 5 figs., 3 tabs.

• OSTI ID: 433040
• Journal Information: Journal of Nuclear Medicine, Vol. 37, Issue 11; Other Information: PBD: Nov 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
BRAIN
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
IMAGES
COMPARATIVE EVALUATIONS
PATIENTS
SENSITIVITY
TECHNETIUM 99
THALAMUS