Ultraviolet and $gamma$-ray-induced reactions of nucleic acid constituents. Reactions of purines with amines
Journal Article
·
· Photochem. Photobiol., v. 19, no. 1, pp. 21-27
OSTI ID:4319714
Photochemical and gamma -ray induced reactions of purines with amines are described which lead to the appropriate 8-substituted purines. The photoproducts were obtained in yields of up to 100% by the use of a variety of photosensitizers, including peroxides. A free radical mechanism is proposed for these reactions. It is suggested that such reactions may be relevant to the problem of the nature DNA-protein cross-links induced by ultraviolet radiation. (auth)
- Research Organization:
- Weizmann Inst. of Science, Rehovoth, Israel
- NSA Number:
- NSA-29-018193
- OSTI ID:
- 4319714
- Journal Information:
- Photochem. Photobiol., v. 19, no. 1, pp. 21-27, Other Information: Orig. Receipt Date: 30-JUN-74; Bib. Info. Source: UK (United Kingdom (sent to DOE from))
- Country of Publication:
- United Kingdom
- Language:
- English
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