PHYSICOCHEMICAL PROPERTIES OF CIRCULATING RED BLOOD CELLS OF LETHALLY X- IRRADIATED MICE TREATED WITH RAT BONE MARROW
Two months after injection of rat bone marrow into lethally x-irradiated mice (950 r-RBM mice), 100% of the circulating RBC were serologically of the rat type, indicating that the surface molecular configuration of R8C from these experimental mics are of the rat type. The hemoglobin was found to be also very much like the rat type in its ease in crystallization, its alkali denaturation property, its electrophoretic property, and its tendency to form a paracrystalline staff at low temperature. These cells possessed dual osmotic propertiess the relative hemoglobin concentration released when cells were lysed in water was more comparable to the rat type, but its temperature dependency was more comparable to the mouse type. (auth)
- Research Organization:
- Oak Ridge National Lab., Tenn.
- NSA Number:
- NSA-12-008959
- OSTI ID:
- 4318546
- Journal Information:
- Blood (U.S.), Vol. Vol: 12; Other Information: Orig. Receipt Date: 31-DEC-58
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
BONE MARROW TREATMENT OF MICE LETHALLY IRRADIATED WITH GAMMA-RAYS UNDER HIGH DOSE RATE. IV. SUPPLEMENTARY STUDIES
Identification and follow-up of homologous and heterologous bone-marrow transplants in radiation-chimeras