HETEROGENEITY IN THE TURNOVER RATES OF LIVER CHOLESTEROL ESTERS

Journal Article · Wed Jul 01 00:00:00 EDT 1959 · Journal of Biological Chemistry (U.S.)

OSTI ID:4248376

Klein, P D; Martin, R A

Sodium acetate labeled with carbon-14 and a recently developed method of cholesterol ester fractionation were used to investigate the rates at which newly synthesized cholesterol is incorporated into various cholesterol esters in rat liver. Results indicate that the incorporation rates are heterogeneous, differing according to the constituent fatty acids, and that these rates do not represent a simple esteriflcation process in equilibrium with a pool of fatty acids. The pertinence of these findings to the regulation of cholesterol metabolism by the rat is considered. (C.H.)

• Research Organization: Argonne National Lab., Lemont, Ill.
• NSA Number: NSA-13-015013
• OSTI ID: 4248376
• Journal Information: Journal of Biological Chemistry (U.S.), Vol. Vol: 234; Other Information: Orig. Receipt Date: 31-DEC-59
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
ACETATES
BIOCHEMISTRY
CARBON 14
CHEMICAL REACTIONS
CHOLESTEROL
CONTROL
ESTERS
FATTY ACIDS
LABELLED COMPOUNDS
LIPIDS
LIVER
METABOLISM
ORGANIC ACIDS
QUALITATIVE ANALYSIS
QUANTITY RATIO
RATS
REACTION KINETICS
SODIUM COMPOUNDS
TRACER TECHNIQUES