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Title: PET - radiopharmaceutical facilities at Washington University Medical School - an overview

Abstract

The PET program at Washington University has evolved over more than three decades of research and development in the use of positron-emitting isotopes in medicine and biology. In 1962 the installation of the first hospital cyclotron in the USA was accomplished. This first machine was an Allis Chalmers (AC) cyclotron and it was operated until July, 1990. Simultaneously with this cyclotron the authors also ran a Cyclotron Corporation (TCC) CS-15 cyclotron that was purchased in 1977. Both of these cyclotrons were maintained in-house and operated with a relatively small downtime (approximately 3.5%). After the dismantling of the AC machine in 1990, a Japanese Steel Works 16/8 (JSW-16/8) cyclotron was installed in the vault. Whereas the AC cyclotron could only accelerate deuterons (6.2 MeV), the JSW - 16/8 machine can accelerate both protons and deuterons, so all of the radiopharmaceuticals can be produced on either of the two presently owned accelerators. At the end of May 1993, the medical school installed the first clinical Tandem Cascade Accelerator (TCA) a collaboration with Science Research Laboratories (SRL) of Somerville, MA. Preliminary target testing, design and development are presently under way. In 1973, the University installed the first operational PETT device in the country,more » and at present there is a large basic science and clinical research program involving more than a hundred staff in nuclear medicine, radiation sciences, neurology, neurosurgery, psychiatry, cardiology, pulmonary medicine, oncology, and surgery.« less

Authors:
;  [1]
  1. Washington Univ., St. Louis, MO (United States)
Publication Date:
Research Org.:
Brookhaven National Lab., Upton, NY (United States)
OSTI Identifier:
41899
Report Number(s):
BNL-61149; CONF-9309170-
ON: DE95006634; TRN: 95:002194-0048
Resource Type:
Conference
Resource Relation:
Conference: 5. international workshop on targetry and target chemistry, Upton, NY (United States), 19-23 Sep 1993; Other Information: PBD: 1994; Related Information: Is Part Of Proceedings of the Fifth International Workshop on Targetry and Target Chemistry; Dahl, J.R.; Ferrieri, R.; Finn, R.; Schlyer, D.J. [eds.]; PB: 392 p.
Country of Publication:
United States
Language:
English
Subject:
40 CHEMISTRY; 55 BIOLOGY AND MEDICINE, BASIC STUDIES; POSITRON COMPUTED TOMOGRAPHY; ISOTOPE PRODUCTION; RADIOPHARMACEUTICALS; ION BEAM TARGETS; CYCLOTRONS; DESIGN; NUCLEAR MEDICINE; ACCELERATOR FACILITIES

Citation Formats

Dence, C.S., and Welch, M.J. PET - radiopharmaceutical facilities at Washington University Medical School - an overview. United States: N. p., 1994. Web.
Dence, C.S., & Welch, M.J. PET - radiopharmaceutical facilities at Washington University Medical School - an overview. United States.
Dence, C.S., and Welch, M.J. Sat . "PET - radiopharmaceutical facilities at Washington University Medical School - an overview". United States.
@article{osti_41899,
title = {PET - radiopharmaceutical facilities at Washington University Medical School - an overview},
author = {Dence, C.S. and Welch, M.J.},
abstractNote = {The PET program at Washington University has evolved over more than three decades of research and development in the use of positron-emitting isotopes in medicine and biology. In 1962 the installation of the first hospital cyclotron in the USA was accomplished. This first machine was an Allis Chalmers (AC) cyclotron and it was operated until July, 1990. Simultaneously with this cyclotron the authors also ran a Cyclotron Corporation (TCC) CS-15 cyclotron that was purchased in 1977. Both of these cyclotrons were maintained in-house and operated with a relatively small downtime (approximately 3.5%). After the dismantling of the AC machine in 1990, a Japanese Steel Works 16/8 (JSW-16/8) cyclotron was installed in the vault. Whereas the AC cyclotron could only accelerate deuterons (6.2 MeV), the JSW - 16/8 machine can accelerate both protons and deuterons, so all of the radiopharmaceuticals can be produced on either of the two presently owned accelerators. At the end of May 1993, the medical school installed the first clinical Tandem Cascade Accelerator (TCA) a collaboration with Science Research Laboratories (SRL) of Somerville, MA. Preliminary target testing, design and development are presently under way. In 1973, the University installed the first operational PETT device in the country, and at present there is a large basic science and clinical research program involving more than a hundred staff in nuclear medicine, radiation sciences, neurology, neurosurgery, psychiatry, cardiology, pulmonary medicine, oncology, and surgery.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1994},
month = {12}
}

Conference:
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