The Mutual Relationship of Spleen and Bone Marrow in Radiation Reactions. III. The Effect of the Spleen on the Reaction Pattern of Bone Marrow After Whole-Body Irradiation

Journal Article · Sun May 01 00:00:00 EDT 1960 · Fortschr. Gebiete Rontgenstrahlen u. Nuklearmed.

DOI:https://doi.org/10.1055/s-0029-1226560· OSTI ID:4185064

Bauer, R; Hartweg, H

The peripheral leucocytosis which is observed after splenectomy is unaccompanied by any demonstrable change in the bone marrow. Splenectomised animals, on the other hand, show earlier and more intense regeneration of blood-forming foci after total body radiation than do omentectomised or irradiated control animals. The differences in the phases of marrow regeneration found in totally and partially irradiated animals are discussed. The previously demonstrated release effect of splenectomy on the bone marrow depends on the functional state of the latter. Finally, resting marrow is apparently not affected, or at least not demonstrably so; proliferating marrow shows a marked and prolonged effect.

• Research Organization: Universitat, Tubingen, Ger.
• Sponsoring Organization: USDOE
• NSA Number: NSA-14-015538
• OSTI ID: 4185064
• Journal Information: Fortschr. Gebiete Rontgenstrahlen u. Nuklearmed., Vol. Vol: 92; Other Information: Orig. Receipt Date: 31-DEC-60
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

BIOLOGY AND MEDICINE
ANIMALS
BLOOD FORMATION
BODY
BONE MARROW
IRRADIATION
LEUCOCYTES
QUANTITY RATIO
RADIATION EFFECTS
REGENERATION
SPLEEN
SPLENECTOMY
STANDARDS
SURGERY
VARIATIONS