SHOCK TUBE STUDIES OF THE EFFECTS OF SHARP-RISING, LONG-DURATION OVER- PRESSURES ON BIOLOGICAL SYSTEMS. Progress Report
A closed-end shock tube was used to study the effects of single and step- wise, fast-rising overpressures of long duration on mice, rats, guinea pigs, and rabbits. For animals exposed side-on against the end-plate to single, sharp- rising pressure pulses, the reflected pressures necessary to kill 50 per cent (LD/ sub 50/) were as follows: for the mouse-29.8 1.l; rabbit-33.4 1.2; guinea pig36.7 0.7; and the rat-38.7 0.6 psi. Animals located at short distances away from the end-plate were loaded in a two-step manner. The steps corresponded to the incident and reflected shock fronts. With stepwise increases in pressure, animals tolerated much higher reflected overpressures than when the pressure load consisted of a single, sharp-rising pulse. The importance of the time interval between step loads was pointed out and briefly discussed. (auth)
- Research Organization:
- Lovelace Foundation for Medical Education and Research, Albuquerque, N. Mex.
- DOE Contract Number:
- AT(29-1)-1242
- NSA Number:
- NSA-15-003821
- OSTI ID:
- 4139705
- Report Number(s):
- TID-6056
- Resource Relation:
- Other Information: Orig. Receipt Date: 31-DEC-61
- Country of Publication:
- United States
- Language:
- English
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