BIOLOGICAL AND MEDICAL RESEARCH DIVISION SEMIANNUAL REPORT, JULY THROUGH DECEMBER, 1959

Technical Report · Thu Dec 01 00:00:00 EST 1960

DOI:https://doi.org/10.2172/4075707· OSTI ID:4075707

Progress is reported on the following studies: the possible relationship between environmental Ra/sup 226/ and incidence of bone tumors in human populations; the incidence of tumors in mice exposed to chronic gamma irradiation; the effects of chronic gamma irradiation on histology of testes cells; the effects of periodic exposure to gamma radiation on the mortality of guinea pigs; determinations of the density of various mouse tissues; the synthesis of dimethyl formarmide (DMF) and uranyl nitrate-DMF; an investigation of the role of the small intestine in acute radiation death in mice following exposure to fast neutrons or gamma radiation; the effect of neutron dose on the incidence of mammary tumors and fertility of female rats and mice; measurements of Cs/sup 137/ in samples of tea and human milk made with a gamma spectrometer; the latency and growth of bone tumors induced by injected Sr/sup 90/ in two strains of mice; histopathologic changes in the skeleton of mice following injection of various doses of Ra/sup 226/ the development of mathematical models of cellular populations; reaction mechanisms in the response of chicks to radiation injuries; cell generation times in E. coli; the demonstration of infective organisms living in the cytoplasm of A. proteus; electron microscopic study of the fine structure of fat cells as related to structure; the effects of enzymes on induction of bacteriophage of E. coli; lipid metabolism and the isolation, fractionation, and analysis of cholesterol esters obtained during turnover studies; tracer studies on the role of urea in nitrogen metabolism using deuterium-labeled urea in which free energies of formation for deuterm-urea were determined; the participation of metal ions in transmethylation activity of enzymes in microorganisms; the effects of ultraviolet irradiation on yeast cells; the effects of thiol compounds on mitochondrial swelling; the effects of photoperiodism on flowering of xanthium; the effects of concentrations of 30 to 50% of deuterium oxide in drinking water on cells of male reproductive organs in mice and dogs and reproductive potential of male mice; the use of tritiated thymidine as a tracer in cell renewal in acute and chronic myelogenous leukemia; the loss of mutagenic potential in chemostat cultures of E. coli;, radioinduced recessive mutations in nince; the demonstration of a recessive mutation in Drosophila; the pathology of ectromelia (a virus disease) and pseudomonas infections in mice; the effects of x, gamma , and neutron irradiation on the formation of bacterial endotoxins in mice; the radioprotective effects of injected protoplasm in amoebas; the effects of chelating agents on the removal of monomeric and polymeric thorium in rats; the relationship of plutonium removal to tumor incidence in mice; the effects of chelating agents on the removal of monomeric and polymenic plutonium in mice; and the use-of tritiated thymidine to measure the growth of tumor metastases in mics. A list of publications during the period is included. (For preceding period see ANL-6200.) (C.H.)

• Research Organization: Argonne National Lab., Ill.
• DOE Contract Number: W-31-109-ENG-38
• NSA Number: NSA-15-012674
• OSTI ID: 4075707
• Report Number(s): ANL-6264
• Resource Relation: Other Information: Orig. Receipt Date: 31-DEC-61
• Country of Publication: United States
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
ALCOHOLS
AMIDES
AMINO ACIDS
AMOEBA
ANIMAL CELLS
BACTERIA
BACTERIOPHAGES
BONES
CESIUM 137
CHELATES
CHOLESTEROL
CYTOLOGY
DENSITY
DEUTERIUM
DISEASES
ELECTRON MICROSCOPY
ENZYMES
ESTERS
FAST NEUTRONS
GAMMA RADIATION
GAMMA SPECTROMETERS
GENETICS
GONADS
GUINEA PIGS
INFECTIONS
INSECTS
INTESTINE
IONS
LEUKEMIA
LIFETIME
LIGHT
LIPIDS
MAN
MATHEMATICS
METABOLISM
METALS
METASTASES
MICE
MILK
MUTATIONS
NITROGEN
ORGANIC SULFUR COMPOUNDS
PLANTS
PLUTONIUM
POPULATIONS
RADIATION EFFECTS
RADIATION INJURIES
RADIATION PROTECTION
RADIATION SICKNESS
RADIUM 226
RATS
REPRODUCTION
THIOLS
THORIUM
TISSUES
TOXICITY
TRAC