skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Mice and men: Making the most of our similarities

Journal Article · · Oak Ridge National Laboratory Review
OSTI ID:35640

Because a big chunk of the genetic information that goes into building a mouse is also needed to put together a human, mice are often employed in the laboratory as genetic stunt doubles for man. In fact, the similarities between sections of human and mouse DNA enable researchers working with mouse genes to make surprisingly accurate predictions about the location and function of their human counterparts. For over 40 years, ORNL researchers have been studying the nuances of the genetic relationship between mice and humans, sometimes with considerable fanfare, other times in relative obscurity, but always with the goals of increasing the understanding of the subtle language of genetics and improving human lives. Some of the laboratory`s latest research in this area is described in this article.

OSTI ID:
35640
Journal Information:
Oak Ridge National Laboratory Review, Vol. 27, Issue 1-2; Other Information: PBD: 1994
Country of Publication:
United States
Language:
English

Similar Records

Inborn anemias in mice: (Annual report, 1983-1984)
Technical Report · Sat Sep 01 00:00:00 EDT 1984 · OSTI ID:35640

Mutation frequencies in male mice and the estimation of genetic hazards of radiation in men
Journal Article · Fri Jan 01 00:00:00 EST 1982 · Proc. Natl. Acad. Sci. U.S.A.; (United States) · OSTI ID:35640

Mutation frequencies in male mice and the estimation of genetic hazards of radiation in men: (specific-locus mutations/dose-rate effect/doubling dose/risk estimation)
Journal Article · Fri Jan 01 00:00:00 EST 1982 · Proc. Natl. Acad. Sci. U.S.A.; (United States) · OSTI ID:35640