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Title: Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same

Abstract

A complex and method for making a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids. 20 figs.

Inventors:
; ; ;
Publication Date:
Research Org.:
Univ. of Missouri, Columbia, MO (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
321196
Patent Number(s):
US 5,843,993/A/
Application Number:
PAN: 8-818,078; TRN: 99:003302
Assignee:
Univ. of Missouri, Columbia, MO (United States)
DOE Contract Number:  
FG02-89ER60875
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 1 Dec 1998
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; 40 CHEMISTRY; DIAGNOSTIC USES; THERAPEUTIC USES; LIGANDS; RADIOPHARMACEUTICALS; GOLD; COMPLEXES; PHOSPHINES

Citation Formats

Katti, K V, Berning, D E, Volkert, W A, and Ketring, A R. Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same. United States: N. p., 1998. Web.
Katti, K V, Berning, D E, Volkert, W A, & Ketring, A R. Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same. United States.
Katti, K V, Berning, D E, Volkert, W A, and Ketring, A R. Tue . "Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same". United States.
@article{osti_321196,
title = {Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same},
author = {Katti, K V and Berning, D E and Volkert, W A and Ketring, A R},
abstractNote = {A complex and method for making a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids. 20 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {12}
}