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U.S. Department of Energy
Office of Scientific and Technical Information

Restoration of normal phenotype in cancer cells

Patent ·
OSTI ID:321195

A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying {beta}{sub 1} integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Human breast epithelial cells were shown to be particularly responsive. 14 figs.

Research Organization:
University of California
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
AC03-76SF00098
Assignee:
Univ. of California, Oakland, CA (United States)
Patent Number(s):
US 5,846,536/A/
Application Number:
PAN: 8-726,230
OSTI ID:
321195
Country of Publication:
United States
Language:
English