Co-factor activated recombinant adenovirus proteinases

Patent · Tue Aug 06 00:00:00 EDT 1996

OSTI ID:288025

Anderson, C W; Mangel, W F

This application describes methods and expression constructs for producing activatable recombinant adenovirus proteinases. Purified activatable recombinant adenovirus proteinases and methods of purification are described. Activated adenovirus proteinases and methods for obtaining activated adenovirus proteinases are further included. Isolated peptide cofactors of adenovirus proteinase activity, methods of purifying and identifying the peptide cofactors are also described. Antibodies immunoreactive with adenovirus proteinases, immunospecific antibodies, and methods for preparing them are also described. Other related methods and materials are also described. 29 figs.

• Research Organization: Associated Universities Inc
• DOE Contract Number: AC02-76CH00016
• Assignee: Associated Universities, Inc., Washington, DC (United States)
• Patent Number(s): US 5,543,264/A/
• Application Number: PAN: 8-155,171
• OSTI ID: 288025
• Resource Relation: Other Information: PBD: 6 Aug 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
PEPTIDE HYDROLASES
CHEMICAL PREPARATION
ADENOVIRUS
ANTIBODIES
ENZYME ACTIVITY
IMMUNE REACTIONS