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Title: Co-factor activated recombinant adenovirus proteinases

Abstract

This application describes methods and expression constructs for producing activatable recombinant adenovirus proteinases. Purified activatable recombinant adenovirus proteinases and methods of purification are described. Activated adenovirus proteinases and methods for obtaining activated adenovirus proteinases are further included. Isolated peptide cofactors of adenovirus proteinase activity, methods of purifying and identifying the peptide cofactors are also described. Antibodies immunoreactive with adenovirus proteinases, immunospecific antibodies, and methods for preparing them are also described. Other related methods and materials are also described. 29 figs.

Inventors:
;
Publication Date:
Research Org.:
Associated Universities Inc
OSTI Identifier:
288025
Patent Number(s):
US 5,543,264/A/
Application Number:
PAN: 8-155,171
Assignee:
Associated Universities, Inc., Washington, DC (United States) PTO; SCA: 550200; PA: EDB-96:137351; SN: 96001636045
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 6 Aug 1996
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; PEPTIDE HYDROLASES; CHEMICAL PREPARATION; ADENOVIRUS; ANTIBODIES; ENZYME ACTIVITY; IMMUNE REACTIONS

Citation Formats

Anderson, C.W., and Mangel, W.F. Co-factor activated recombinant adenovirus proteinases. United States: N. p., 1996. Web.
Anderson, C.W., & Mangel, W.F. Co-factor activated recombinant adenovirus proteinases. United States.
Anderson, C.W., and Mangel, W.F. Tue . "Co-factor activated recombinant adenovirus proteinases". United States.
@article{osti_288025,
title = {Co-factor activated recombinant adenovirus proteinases},
author = {Anderson, C.W. and Mangel, W.F.},
abstractNote = {This application describes methods and expression constructs for producing activatable recombinant adenovirus proteinases. Purified activatable recombinant adenovirus proteinases and methods of purification are described. Activated adenovirus proteinases and methods for obtaining activated adenovirus proteinases are further included. Isolated peptide cofactors of adenovirus proteinase activity, methods of purifying and identifying the peptide cofactors are also described. Antibodies immunoreactive with adenovirus proteinases, immunospecific antibodies, and methods for preparing them are also described. Other related methods and materials are also described. 29 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1996},
month = {8}
}