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Title: A 2D smart pixel detector for time-resolved protein crystallography

Conference ·
OSTI ID:251594

A smart pixel detector is being developed for Time Resolved Crystallography for biological and material science applications. Using the Pixel detector presented here, the Laue method will enable the study of the evolution of structural changes that occur within the protein as a function of time. The x-ray pixellated detector is assembled to the integrated circuit through a bump bonding process. Within a pixel size of 150 x 150 {mu}m{sup 2}, a low noise preamplifier-shaper, a discriminator, a 3 bit counter and the readout logic are integrated. The readout, based on the Column Architecture principle, will accept hit rates above 5x10{sup 8}/cm{sup 2}/s with a maximum hit rate per pixel of 1 MHz. This detector will allow time resolved Laue crystallography to be performed in a frameless operation mode, without dead time. Target specifications, architecture, and preliminary results on the 8 x 8 front-end prototype and column readout are presented.

Research Organization:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
AC03-76SF00098
OSTI ID:
251594
Report Number(s):
LBL-37542; LSBL-297; CONF-9510119-37; ON: DE96011511
Resource Relation:
Conference: SRI `95: synchrotron radiation instrumentation symposium and the 7. users meeting for the advanced photon source (APS), Argonne, IL (United States), 16-20 Oct 1995; Other Information: PBD: Oct 1995
Country of Publication:
United States
Language:
English