Pb(II) coordination to the nonclassical zinc finger tristetraprolin: retained function with an altered fold

Stoltzfus, Andrew T.; Campbell, Courtney J.; Worth, Madison M.; Hom, Kellie; Stemmler, Timothy L.; Michel, Sarah L.  J.

doi:10.1007/s00775-022-01980-1

Pb(II) coordination to the nonclassical zinc finger tristetraprolin: retained function with an altered fold

Journal Article · 07 December 2022 · JBIC Journal of Biological Inorganic Chemistry

DOI:https://doi.org/10.1007/s00775-022-01980-1· OSTI ID:2423917

Stoltzfus, Andrew T.; Campbell, Courtney J.; Worth, Madison M.; Hom, Kellie; Stemmler, Timothy L.; Michel, Sarah L. J.

Not provided.

Research Organization:: SLAC National Accelerator Laboratory, Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-76SF00515

OSTI ID:: 2423917

Journal Information:: JBIC Journal of Biological Inorganic Chemistry, Journal Name: JBIC Journal of Biological Inorganic Chemistry Journal Issue: 1 Vol. 28; ISSN 1432-1327

Publisher:: Springer

Country of Publication:: United States

Language:: English

References (96)

Defining potential roles of Pb²⁺in neurotoxicity from a calciomics approach Gorkhali, Rakshya; Huang, Kenneth; Kirberger, Michael Metallomics, Vol. 8, Issue 6 https://doi.org/10.1039/C6MT00038J	journal	January 2016
Utilization of a Synthetic Peptide as a Tool to Study the Interaction of Heavy Metals with the Zinc Finger Domain of Proteins Critical for Gene Expression in the Developing Brain Razmiafshari, Morad; Zawia, Nasser H. Toxicology and Applied Pharmacology, Vol. 166, Issue 1 https://doi.org/10.1006/taap.2000.8950	journal	July 2000
Spectroscopic and Functional Determination of the Interaction of Pb ²⁺ with GATA Proteins Ghering, Amy B.; Miller Jenkins, Lisa M.; Schenck, Brandy L. Journal of the American Chemical Society, Vol. 127, Issue 11 https://doi.org/10.1021/ja0464544	journal	March 2005
Are free radicals involved in lead poisoning? Hermes-Lima, M.; Pereira, B.; Bechara, E. J. H. Xenobiotica, Vol. 21, Issue 8 https://doi.org/10.3109/00498259109039548	journal	January 1991
The biological chemistry of lead Godwin, Hilary Arnold Current Opinion in Chemical Biology, Vol. 5, Issue 2 https://doi.org/10.1016/S1367-5931(00)00194-0	journal	April 2001
Hard and Soft Acids and Bases Pearson, Ralph G. Journal of the American Chemical Society, Vol. 85, Issue 22 https://doi.org/10.1021/ja00905a001	journal	November 1963
Metalation of metallothioneins Ngu, Thanh T.; Stillman, Martin J. IUBMB Life, Vol. 61, Issue 4 https://doi.org/10.1002/iub.182	journal	March 2009
Zinc Finger Proteins in Neuro-Related Diseases Progression Bu, Siyuan; Lv, Yihan; Liu, Yusheng Frontiers in Neuroscience, Vol. 15 https://doi.org/10.3389/fnins.2021.760567	journal	November 2021
e-Cigarette Use Among Youth in the United States, 2019 Cullen, Karen A.; Gentzke, Andrea S.; Sawdey, Michael D. JAMA, Vol. 322, Issue 21 https://doi.org/10.1001/jama.2019.18387	journal	December 2019
A Cys₃His Zinc-Binding Domain from Nup475/Tristetraprolin: A Novel Fold with a Disklike Structure Amann, Barbara T.; Worthington, Mark T.; Berg, Jeremy M. Biochemistry, Vol. 42, Issue 1 https://doi.org/10.1021/bi026988m	journal	December 2002
GATA family transcriptional factors: emerging suspects in hematologic disorders Gao, Juehua; Chen, Yi-Hua; Peterson, LoAnn C. Experimental Hematology & Oncology, Vol. 4, Issue 1 https://doi.org/10.1186/s40164-015-0024-z	journal	October 2015
Locating the Binding Sites of Pb(II) Ion with Human and Bovine Serum Albumins Belatik, Ahmed; Hotchandani, Surat; Carpentier, Robert PLoS ONE, Vol. 7, Issue 5 https://doi.org/10.1371/journal.pone.0036723	journal	May 2012
Impact of naturally occurring serine/cysteine variations on the structure and function of Pseudomonas metallothioneins Habjanič, Jelena; Chesnov, Serge; Zerbe, Oliver Metallomics, Vol. 12, Issue 1 https://doi.org/10.1039/c9mt00213h	journal	November 2019
Spectroscopic characterization of copper(I) binding to apo and metal-reconstituted zinc finger peptides Doku, Reginald T.; Park, Grace; Wheeler, Korin E. JBIC Journal of Biological Inorganic Chemistry, Vol. 18, Issue 6 https://doi.org/10.1007/s00775-013-1012-6	journal	June 2013
Spectroscopic Properties of the Metalloregulatory Cd(II) and Pb(II) Sites of S. aureus pI258 CadC Busenlehner, Laura S.; Cosper, Nathaniel J.; Scott, Robert A. Biochemistry, Vol. 40, Issue 14 https://doi.org/10.1021/bi010006g	journal	March 2001
Co(II) Coordination in Prokaryotic Zinc Finger Domains as Revealed by UV-Vis Spectroscopy Sivo, Valeria; D’Abrosca, Gianluca; Russo, Luigi Bioinorganic Chemistry and Applications, Vol. 2017 https://doi.org/10.1155/2017/1527247	journal	January 2017
Lead and other metals can substitute for Ca2+ in calmodulin Habermann, E.; Crowell, K.; Janicki, P. Archives of Toxicology, Vol. 54, Issue 1 https://doi.org/10.1007/BF00277816	journal	September 1983
Mercury and lead during breast-feeding Dorea, José G. British Journal of Nutrition, Vol. 92, Issue 1 https://doi.org/10.1079/BJN20041163	journal	July 2004
Zinc Finger Proteins as Potential Targets for Toxic Metal Ions: Differential Effects on Structure and Function Hartwig, Andrea Antioxidants & Redox Signaling, Vol. 3, Issue 4 https://doi.org/10.1089/15230860152542970	journal	August 2001
Cu(I) Disrupts the Structure and Function of the Nonclassical Zinc Finger Protein Tristetraprolin (TTP) Shimberg, Geoffrey D.; Ok, Kiwon; Neu, Heather M. Inorganic Chemistry, Vol. 56, Issue 12 https://doi.org/10.1021/acs.inorgchem.7b00125	journal	May 2017
Zinc-finger proteins in health and disease Cassandri, Matteo; Smirnov, Artem; Novelli, Flavia Cell Death Discovery, Vol. 3, Issue 1 https://doi.org/10.1038/cddiscovery.2017.71	journal	November 2017
Zn(II) Binding and DNA Binding Properties of Ligand-Substituted CXHH-Type Zinc Finger Proteins Imanishi, Miki; Matsumura, Kazushi; Tsuji, Shogo Biochemistry, Vol. 51, Issue 16 https://doi.org/10.1021/bi300236m	journal	April 2012
Lead exposure alters Egr‐1 DNA‐binding in the neonatal rat brain Reddy, G. R.; Zawia, N. H. International Journal of Developmental Neuroscience, Vol. 18, Issue 8 https://doi.org/10.1016/S0736-5748(00)00048-4	journal	December 2000
RNA binding proteins in the control of autoimmune diseases Yoshinaga, Masanori; Takeuchi, Osamu Immunological Medicine, Vol. 42, Issue 2 https://doi.org/10.1080/25785826.2019.1655192	journal	April 2019
The Paradox of Lead Poisoning Prevention Lanphear, Bruce P. Science, Vol. 281, Issue 5383 https://doi.org/10.1126/science.281.5383.1617	journal	September 1998
Similarities between N-Acetylcysteine and Glutathione in Binding to Lead(II) Ions Sisombath, Natalie S.; Jalilehvand, Farideh Chemical Research in Toxicology, Vol. 28, Issue 12 https://doi.org/10.1021/acs.chemrestox.5b00323	journal	December 2015
Spectroscopic characterization of Co(II)-, Ni(II)-, and Cd(II)-substituted wild-type and non-native retroviral-type zinc finger peptides Chen, X.; Chu, M.; Giedroc, D. P. JBIC Journal of Biological Inorganic Chemistry, Vol. 5, Issue 1 https://doi.org/10.1007/s007750050012	journal	February 2000
Ligand variation and metal ion binding specificity in zinc finger peptides Krizek, Beth Allyn; Merkle, Denise L.; Berg, Jeremy M. Inorganic Chemistry, Vol. 32, Issue 6 https://doi.org/10.1021/ic00058a030	journal	March 1993
Cadmium Exchange with Zinc in the Non-Classical Zinc Finger Protein Tristetraprolin Brandis, Joel E. P.; Zalesak, Stephanie M.; Kane, Maureen A. Inorganic Chemistry, Vol. 60, Issue 11 https://doi.org/10.1021/acs.inorgchem.0c03808	journal	May 2021
Early (in uterus and infant) exposure to mercury and lead Dorea, Jose G.; Donangelo, Carmen M. Clinical Nutrition, Vol. 25, Issue 3 https://doi.org/10.1016/j.clnu.2005.10.007	journal	June 2006
Vaping: The new wave of nicotine addiction Dinardo, Perry; Rome, Ellen S. Cleveland Clinic Journal of Medicine, Vol. 86, Issue 12 https://doi.org/10.3949/ccjm.86a.19118	journal	December 2019
Bacterial metallothioneins: past, present, and questions for the future Blindauer, Claudia A. JBIC Journal of Biological Inorganic Chemistry, Vol. 16, Issue 7 https://doi.org/10.1007/s00775-011-0790-y	journal	May 2011
Peptidic models for the binding of Pb(II), Bi(III) and Cd(II) to mononuclear thiolate binding sites Matzapetakis, Manolis; Ghosh, Debdip; Weng, Tsu-Chien JBIC Journal of Biological Inorganic Chemistry, Vol. 11, Issue 7 https://doi.org/10.1007/s00775-006-0140-7	journal	July 2006
Fe-S clusters masquerading as zinc finger proteins Pritts, Jordan D.; Michel, Sarah L. J. Journal of Inorganic Biochemistry, Vol. 230 https://doi.org/10.1016/j.jinorgbio.2022.111756	journal	May 2022
The Cross-talk between Tristetraprolin and Cytokines in Cancer Guo, Jian; Wang, Hao; Jiang, Shiyi Anti-Cancer Agents in Medicinal Chemistry, Vol. 17, Issue 11 https://doi.org/10.2174/1871520617666170327155124	journal	November 2017
Mechanisms of divalent metal toxicity in affective disorders Menon, Archita Venugopal; Chang, JuOae; Kim, Jonghan Toxicology, Vol. 339 https://doi.org/10.1016/j.tox.2015.11.001	journal	January 2016
Spectral properties of cobalt carboxypeptidase. Effects of substrates and inhibitors Latt, S. A.; Vallee, B. L. Biochemistry, Vol. 10, Issue 23 https://doi.org/10.1021/bi00799a017	journal	November 1971
Tristetraprolin specifically regulates the expression and alternative splicing of immune response genes in HeLa cells Tu, Yafang; Wu, Xiongfei; Yu, Fengyun BMC Immunology, Vol. 20, Issue 1 https://doi.org/10.1186/s12865-019-0292-1	journal	May 2019
Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer’s disease Alkallas, Rached; Fish, Lisa; Goodarzi, Hani Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/s41467-017-00867-z	journal	October 2017
Tristetraprolin destabilizes NOX2 mRNA and protects dopaminergic neurons from oxidative damage in Parkinson's disease Sun, Xiang; Zhang, Hongbo; Xie, Linghai The FASEB Journal, Vol. 34, Issue 11 https://doi.org/10.1096/fj.201902967R	journal	September 2020
Elucidation of Primary (α3N) and Vestigial (α5) Heavy Metal-binding Sites in Staphylococcus aureus pI258 CadC: Evolutionary Implications for Metal Ion Selectivity of ArsR/SmtB Metal Sensor Proteins Busenlehner, Laura S.; Weng, Tsu-Chien; Penner-Hahn, James E. Journal of Molecular Biology, Vol. 319, Issue 3 https://doi.org/10.1016/S0022-2836(02)00299-1	journal	June 2002
Structural differences between Pb2+- and Ca2+-binding sites in proteins: Implications with respect to toxicity Kirberger, Michael; Yang, Jenny J. Journal of Inorganic Biochemistry, Vol. 102, Issue 10 https://doi.org/10.1016/j.jinorgbio.2008.06.014	journal	October 2008
Pb-207 NMR spectroscopy reveals that Pb(II) coordinates with glutathione (GSH) and tris cysteine zinc finger proteins in a PbS3 coordination environment Neupane, Kosh P.; Pecoraro, Vincent L. Journal of Inorganic Biochemistry, Vol. 105, Issue 8 https://doi.org/10.1016/j.jinorgbio.2011.04.010	journal	August 2011
Cysteine and histidine shuffling: mixing and matching cysteine and histidine residues in zinc finger proteins to afford different folds and function Michalek, Jamie L.; Besold, Angelique N.; Michel, Sarah L. J. Dalton Transactions, Vol. 40, Issue 47 https://doi.org/10.1039/c1dt11071c	journal	January 2011
Further insights into the metal ion binding abilities and the metalation pathway of a plant metallothionein from Musa acuminata Cabral, Augusto C. S.; Jakovleska, Jovana; Deb, Aniruddha JBIC Journal of Biological Inorganic Chemistry, Vol. 23, Issue 1 https://doi.org/10.1007/s00775-017-1513-9	journal	December 2017
Role of Gold in Inflammation and Tristetraprolin Activity Ok, Kiwon; Li, Wenjing; Neu, Heather M. Chemistry – A European Journal, Vol. 26, Issue 7 https://doi.org/10.1002/chem.201904837	journal	January 2020
Inhibition of Transcription Factor IIIA-DNA Interactions by Xenobiotic Metal Ions Hanas, J. S.; Gunn, C. G. Nucleic Acids Research, Vol. 24, Issue 5 https://doi.org/10.1093/nar/24.5.924	journal	January 1996
XAFS of dinuclear metal sites in proteins and model compounds Riggs-Gelasco, Pamela J.; Stemmler, Timothy L.; Penner-Hahn, James E. Coordination Chemistry Reviews, Vol. 144 https://doi.org/10.1016/0010-8545(95)01144-E	journal	October 1995
Blood Lead Levels Among Children Aged <6 Years — Flint, Michigan, 2013–2016 Kennedy, Chinaro; Yard, Ellen; Dignam, Timothy MMWR. Morbidity and Mortality Weekly Report, Vol. 65, Issue 25 https://doi.org/10.15585/mmwr.mm6525e1	journal	July 2016
Unraveling the RNA Binding Properties of the Iron–Sulfur Zinc Finger Protein CPSF30 Pritts, Jordan D.; Hursey, Matthew S.; Michalek, Jamie L. Biochemistry, Vol. 59, Issue 8 https://doi.org/10.1021/acs.biochem.9b01065	journal	February 2020
Lead(II) Complex Formation with Glutathione Mah, Vicky; Jalilehvand, Farideh Inorganic Chemistry, Vol. 51, Issue 11 https://doi.org/10.1021/ic300496t	journal	May 2012
Counting the Zinc-Proteins Encoded in the Human Genome Andreini, Claudia; Banci, Lucia; Bertini, Ivano Journal of Proteome Research, Vol. 5, Issue 1 https://doi.org/10.1021/pr050361j	journal	January 2006
On the metal ion specificity of zinc finger proteins Berg, Jeremy M.; Merkle, Denise L. Journal of the American Chemical Society, Vol. 111, Issue 10 https://doi.org/10.1021/ja00192a050	journal	May 1989
Activation of troponin C by Cd2+ and Pb2+ Chao, ShengHao; Bu, Chun -Hui; Cheung, Wai Yiu Archives of Toxicology, Vol. 64, Issue 6 https://doi.org/10.1007/BF01977632	journal	August 1990
Pb(ii) binding to the brain specific mammalian metallothionein isoform MT3 and its isolated αMT3 and βMT3 domains Pérez-Zúñiga, Catalina; Leiva-Presa, Àngels; Austin, Rachel Narehood Metallomics, Vol. 11, Issue 2 https://doi.org/10.1039/C8MT00294K	journal	January 2019
A Pathogenetic Role for TNFα in the Syndrome of Cachexia, Arthritis, and Autoimmunity Resulting from Tristetraprolin (TTP) Deficiency Taylor, Gregory A.; Carballo, Ester; Lee, David M. Immunity, Vol. 4, Issue 5 https://doi.org/10.1016/S1074-7613(00)80411-2	journal	May 1996
Lead Exposures in U.S. Children, 2008: Implications for Prevention Levin, Ronnie; Brown, Mary Jean; Kashtock, Michael E. Environmental Health Perspectives, Vol. 116, Issue 10 https://doi.org/10.1289/ehp.11241	journal	October 2008
Global approach to reducing lead exposure and poisoning Meyer, P.; Brown, M.; Falk, H. Mutation Research/Reviews in Mutation Research, Vol. 659, Issue 1-2 https://doi.org/10.1016/j.mrrev.2008.03.003	journal	July 2008
Functional Characterization of Iron-Substituted Tristetraprolin-2D (TTP-2D, NUP475-2D): RNA Binding Affinity and Selectivity diTargiani, Robert C.; Lee, Seung Jae; Wassink, Sarah Biochemistry, Vol. 45, Issue 45 https://doi.org/10.1021/bi060747n	journal	October 2006
GATA transcription factors in the developing and adult heart Pikkarainen, S. Cardiovascular Research, Vol. 63, Issue 2 https://doi.org/10.1016/j.cardiores.2004.03.025	journal	August 2004
Characteristics of the Interaction of a Synthetic Human Tristetraprolin Tandem Zinc Finger Peptide with AU-rich Element-containing RNA Substrates Blackshear, Perry J.; Lai, Wi S.; Kennington, Elizabeth A. Journal of Biological Chemistry, Vol. 278, Issue 22 https://doi.org/10.1074/jbc.M301290200	journal	May 2003
Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d Hudson, Brian P.; Martinez-Yamout, Maria A.; Dyson, H. Jane Nature Structural & Molecular Biology, Vol. 11, Issue 3 https://doi.org/10.1038/nsmb738	journal	February 2004
Targeting Zinc Finger Proteins with Exogenous Metals and Molecules: Lessons Learned from Tristetraprolin, a CCCH type Zinc Finger Ok, Kiwon; Filipovic, Milos R.; Michel, Sarah L. J. European Journal of Inorganic Chemistry, Vol. 2021, Issue 37 https://doi.org/10.1002/ejic.202100402	journal	July 2021
Cadmium coordination to the zinc binding domains of the non-classical zinc finger protein Tristetraprolin affects RNA binding selectivity Michalek, Jamie L.; Lee, Seung Jae; Michel, Sarah L. J. Journal of Inorganic Biochemistry, Vol. 112 https://doi.org/10.1016/j.jinorgbio.2012.02.023	journal	July 2012
Roles of Tristetraprolin in Tumorigenesis Park, Jeong-Min; Lee, Tae-Hee; Kang, Tae-Hong International Journal of Molecular Sciences, Vol. 19, Issue 11 https://doi.org/10.3390/ijms19113384	journal	October 2018
Structural and Functional Characterization of Mycobacterium tuberculosis CmtR, a Pb ^II /Cd ^II -Sensing SmtB/ArsR Metalloregulatory Repressor Wang, Yun; Hemmingsen, Lars; Giedroc, David P. Biochemistry, Vol. 44, Issue 25 https://doi.org/10.1021/bi050094v	journal	June 2005
Differential effects of toxic metal compounds on the activities of Fpg and XPA, two zinc finger proteins involved in DNA repair Asmuss, M. Carcinogenesis, Vol. 21, Issue 11 https://doi.org/10.1093/carcin/21.11.2097	journal	November 2000
Progress and challenges in the theory and interpretation of X-ray spectra Rehr, J. J.; Ankudinov, A. L. Journal of Synchrotron Radiation, Vol. 8, Issue 2 https://doi.org/10.1107/S0909049500016423	journal	March 2001
Zn-, Cd-, and Pb-transcription factor IIIA: properties, DNA binding, and comparison with TFIIIA-finger 3 metal complexes Huang, Meilin; Krepkiy, Dmitriy; Hu, Weining Journal of Inorganic Biochemistry, Vol. 98, Issue 5 https://doi.org/10.1016/j.jinorgbio.2004.01.014	journal	May 2004
Lead (Pb) Exposure Enhances Expression of Factors Associated with Inflammation Metryka, Emilia; Chibowska, Karina; Gutowska, Izabela International Journal of Molecular Sciences, Vol. 19, Issue 6 https://doi.org/10.3390/ijms19061813	journal	June 2018
Functional characterization of iron-substituted neural zinc finger factor 1: metal and DNA binding Besold, Angelique N.; Lee, Seung Jae; Michel, Sarah L. J. JBIC Journal of Biological Inorganic Chemistry, Vol. 15, Issue 4 https://doi.org/10.1007/s00775-010-0626-1	journal	March 2010
Zinc in the central nervous system: From molecules to behavior Gower-Winter, Shannon D.; Levenson, Cathy W. BioFactors, Vol. 38, Issue 3 https://doi.org/10.1002/biof.1012	journal	March 2012
Structural Metal Sites in Nonclassical Zinc Finger Proteins Involved in Transcriptional and Translational Regulation Lee, Seung Jae; Michel, Sarah L. J. Accounts of Chemical Research, Vol. 47, Issue 8 https://doi.org/10.1021/ar500182d	journal	July 2014
Regulatory Roles of High‐Affinity Metal‐Binding Proteins in Mediating Lead Effects on δ‐Aminolevulinic Acid Dehydratase Goering, Peter L.; Fowler, Bruce A. Annals of the New York Academy of Sciences, Vol. 514, Issue 1 https://doi.org/10.1111/j.1749-6632.1987.tb48778.x	journal	December 1987
Cigalike electronic nicotine delivery systems e-liquids contain variable levels of metals Neu, Heather M.; Lee, Angela; Brandis, Joel E. P. Scientific Reports, Vol. 10, Issue 1 https://doi.org/10.1038/s41598-020-67789-7	journal	July 2020
Neurotoxicity of low-level lead exposure: History, mechanisms of action, and behavioral effects in humans and preclinical models Rocha, Angelica; Trujillo, Keith A. NeuroToxicology, Vol. 73 https://doi.org/10.1016/j.neuro.2019.02.021	journal	July 2019
Cysteine Oxidation Enhanced by Iron in Tristetraprolin, A Zinc Finger Peptide Lee, Seung Jae; Michel, Sarah L. J. Inorganic Chemistry, Vol. 49, Issue 3 https://doi.org/10.1021/ic9024298	journal	January 2010
Lead neurotoxicity: exploring the potential impact of lead substitution in zinc-finger proteins on mental health Ordemann, Jacqueline Michelle; Austin, Rachel Narehood Metallomics, Vol. 8, Issue 6 https://doi.org/10.1039/C5MT00300H	journal	January 2016
Tristetraprolin, Inflammation, and Metabolic Syndrome in Arab Adults: A Case Control Study Al-Daghri, Nasser M.; Al-Shuwaie, Albatul Y. A.; Alghamdi, Amani Biology, Vol. 10, Issue 6 https://doi.org/10.3390/biology10060550	journal	June 2021
Reexamination of Lead(II) Coordination Preferences in Sulfur-Rich Sites: Implications for a Critical Mechanism of Lead Poisoning Magyar, John S.; Weng, Tsu-Chien; Stern, Charlotte M. Journal of the American Chemical Society, Vol. 127, Issue 26 https://doi.org/10.1021/ja0424530	journal	July 2005
Lead Fingers: Pb ²⁺ Binding to Structural Zinc-Binding Domains Determined Directly by Monitoring Lead−Thiolate Charge-Transfer Bands Payne, John C.; ter Horst, Marc A.; Godwin, Hilary Arnold Journal of the American Chemical Society, Vol. 121, Issue 29 https://doi.org/10.1021/ja990899o	journal	July 1999
Regulation of mRNA stability by CCCH-type zinc-finger proteins in immune cells Maeda, Kazuhiko; Akira, Shizuo International Immunology, Vol. 29, Issue 4 https://doi.org/10.1093/intimm/dxx015	journal	March 2017
Lead‐induced developmental perturbations in hippocampal Sp1 DNA‐binding are prevented by zinc supplementation: in vivo evidence for Pb and Zn competition Basha, Md. Riyaz; Wei, Wei; Brydie, Michelle International Journal of Developmental Neuroscience, Vol. 21, Issue 1 https://doi.org/10.1016/S0736-5748(02)00137-5	journal	January 2003
Control of Lead Sources in the United States, 1970-2017: Public Health Progress and Current Challenges to Eliminating Lead Exposure Dignam, Timothy; Kaufmann, Rachel B.; LeStourgeon, Lauren Journal of Public Health Management and Practice, Vol. 25, Issue 1 https://doi.org/10.1097/PHH.0000000000000889	journal	January 2019
The Importance of Stereochemically Active Lone Pairs For Influencing PbII and AsIII Protein Binding Zampella, Giuseppe; Neupane, Kosh P.; De Gioia, Luca Chemistry - A European Journal, Vol. 18, Issue 7 https://doi.org/10.1002/chem.201102786	journal	January 2012
Ni(II), Hg(II), and Pb(II) Coordination in the Prokaryotic Zinc-Finger Ros87 Sivo, Valeria; D’Abrosca, Gianluca; Baglivo, Ilaria Inorganic Chemistry, Vol. 58, Issue 2 https://doi.org/10.1021/acs.inorgchem.8b02201	journal	December 2018
Developmental lead effects on behavior and brain gene expression in male and female BALB/cAnNTac mice Kasten-Jolly, Jane; Pabello, Nina; Bolivar, Valerie J. NeuroToxicology, Vol. 33, Issue 5 https://doi.org/10.1016/j.neuro.2012.04.017	journal	October 2012
Tristetraprolin Prevents Gastric Metaplasia in Mice by Suppressing Pathogenic Inflammation Busada, Jonathan T.; Khadka, Stuti; Peterson, Kylie N. Cellular and Molecular Gastroenterology and Hepatology, Vol. 12, Issue 5 https://doi.org/10.1016/j.jcmgh.2021.07.015	journal	January 2021
Metalloprotein active site structure determination: Synergy between X-ray absorption spectroscopy and X-ray crystallography Cotelesage, Julien J. H.; Pushie, M. Jake; Grochulski, Pawel Journal of Inorganic Biochemistry, Vol. 115 https://doi.org/10.1016/j.jinorgbio.2012.06.019	journal	October 2012
Zinc through the Three Domains of Life Andreini, Claudia; Banci, Lucia; Bertini, Ivano Journal of Proteome Research, Vol. 5, Issue 11 https://doi.org/10.1021/pr0603699	journal	November 2006
Metal toxicity and opportunistic binding of Pb2+ in proteins Kirberger, Michael; Wong, Hing C.; Jiang, Jie Journal of Inorganic Biochemistry, Vol. 125 https://doi.org/10.1016/j.jinorgbio.2013.04.002	journal	August 2013
Flint Water Crisis Caused By Interrupted Corrosion Control: Investigating “Ground Zero” Home Pieper, Kelsey J.; Tang, Min; Edwards, Marc A. Environmental Science & Technology, Vol. 51, Issue 4 https://doi.org/10.1021/acs.est.6b04034	journal	February 2017
Redetermination of ( D -penicillaminato)lead(II) Schell, Adam C.; Parvez, Masood; Jalilehvand, Farideh Acta Crystallographica Section E Structure Reports Online, Vol. 68, Issue 4 https://doi.org/10.1107/S1600536812011877	journal	March 2012
RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins Fu, Mingui; Blackshear, Perry J. Nature Reviews Immunology, Vol. 17, Issue 2 https://doi.org/10.1038/nri.2016.129	journal	December 2016
Selective RNA Binding by a Single CCCH Zinc-Binding Domain from Nup475 (Tristetraprolin) Michel, Sarah L. J.; Guerrerio, Anthony L.; Berg, Jeremy M. Biochemistry, Vol. 42, Issue 16 https://doi.org/10.1021/bi034073h	journal	April 2003
Metal binding properties, stability and reactivity of zinc fingers Kluska, Katarzyna; Adamczyk, Justyna; Krężel, Artur Coordination Chemistry Reviews, Vol. 367 https://doi.org/10.1016/j.ccr.2018.04.009	journal	July 2018

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Pb(II) coordination to the nonclassical zinc finger tristetraprolin: retained function with an altered fold

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