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A family of radical halogenases for the engineering of amino-acid-based products
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journal
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September 2019 |
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Regioselective and Enantioselective Intermolecular Buchner Ring Expansions in Flow
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journal
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September 2017 |
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Modern Organic Synthesis with α-Diazocarbonyl Compounds
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journal
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August 2015 |
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Ligand and counteranion enabled regiodivergent C–H bond functionalization of naphthols with α-aryl-α-diazoesters
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journal
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January 2019 |
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A Gold Catalyst for Carbene‐Transfer Reactions from Ethyl Diazoacetate
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journal
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August 2005 |
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Highly Site-Selective Direct C–H Bond Functionalization of Phenols with α-Aryl-α-diazoacetates and Diazooxindoles via Gold Catalysis
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journal
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May 2014 |
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Highly para‐Selective C−H Alkylation of Benzene Derivatives with 2,2,2‐Trifluoroethyl α‐Aryl‐α‐Diazoesters
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journal
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January 2017 |
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The role of Thr268 in oxygen activation of cytochrome P450BM-3
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November 1995 |
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Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase
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journal
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January 2014 |
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Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism
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journal
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January 2018 |
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Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
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journal
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October 2014 |
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Mechanistic Studies on Gold-Catalyzed Direct Arene C–H Bond Functionalization by Carbene Insertion: The Coinage-Metal Effect
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journal
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October 2016 |
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Exploiting and engineering hemoproteins for abiological carbene and nitrene transfer reactions
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journal
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October 2017 |
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Selective C H bond functionalization with engineered heme proteins: new tools to generate complexity
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journal
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April 2019 |
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Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
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journal
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January 2008 |
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Divergent synthesis of complex diterpenes through a hybrid oxidative approach
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journal
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August 2020 |
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Diversification of aliphatic C–H bonds in small molecules and polyolefins through radical chain transfer
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journal
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February 2022 |
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Navigating the Unnatural Reaction Space: Directed Evolution of Heme Proteins for Selective Carbene and Nitrene Transfer
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journal
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January 2021 |
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Highly Diastereo- and Enantioselective Synthesis of Nitrile-Substituted Cyclopropanes by Myoglobin-Mediated Carbene Transfer Catalysis
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journal
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November 2018 |
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Late-stage C–H functionalization offers new opportunities in drug discovery
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journal
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July 2021 |
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Enantiodivergent α-Amino C–H Fluoroalkylation Catalyzed by Engineered Cytochrome P450s
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journal
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June 2019 |
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Iron and Manganese Catalysts for the Selective Functionalization of Arene C(sp 2 )−H Bonds by Carbene Insertion
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journal
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April 2016 |
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Reducing Codon Redundancy and Screening Effort of Combinatorial Protein Libraries Created by Saturation Mutagenesis
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journal
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June 2012 |
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Structural and Spectroscopic Analysis of the F393H Mutant of Flavocytochrome P450 BM3
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journal
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October 2001 |
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C–H Activation: Toward Sustainability and Applications
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journal
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February 2021 |
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Mechanism of the Selective Fe-Catalyzed Arene Carbon–Hydrogen Bond Functionalization
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journal
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March 2018 |
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Cross-Coupling Reactions Involving Metal Carbene: From C═C/C–C Bond Formation to C–H Bond Functionalization
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journal
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September 2013 |
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Directed Evolution of a Cytochrome P450 Carbene Transferase for Selective Functionalization of Cyclic Compounds
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journal
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May 2019 |
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Diazoacetonitrile (N2CHCN): A Long Forgotten but Valuable Reagent for Organic Synthesis
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journal
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October 2019 |
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Controlled Oxidation of Remote sp 3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity
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journal
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November 2012 |
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Significantly shorter Fe–S bond in cytochrome P450-I is consistent with greater reactivity relative to chloroperoxidase
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journal
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August 2015 |
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Evolved Aliphatic Halogenases Enable Regiocomplementary C−H Functionalization of a Pharmaceutically Relevant Compound
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journal
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November 2019 |
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Myoglobin-Catalyzed C−H Functionalization of Unprotected Indoles
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journal
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July 2018 |
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Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution
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journal
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August 2011 |
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Late-Stage Functionalization
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journal
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August 2020 |
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Site‐Selective Functionalization of (sp 3 )C−H Bonds Catalyzed by Artificial Metalloenzymes Containing an Iridium‐Porphyrin Cofactor
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journal
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September 2019 |
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Electrochemical Aminoxyl-Mediated α-Cyanation of Secondary Piperidines for Pharmaceutical Building Block Diversification
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journal
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August 2018 |
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Catalytic functionalization of low reactive C(sp3)–H and C(sp2)–H bonds of alkanes and arenes by carbene transfer from diazo compounds
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journal
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January 2015 |
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Enantioselective, intermolecular benzylic C–H amination catalysed by an engineered iron-haem enzyme
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journal
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May 2017 |
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Enantioselective cyanation of benzylic C–H bonds via copper-catalyzed radical relay
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journal
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September 2016 |
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Catalytic Carbene Insertion into C−H Bonds
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journal
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February 2010 |
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Undirected, Homogeneous C–H Bond Functionalization: Challenges and Opportunities
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journal
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May 2016 |
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Tryptamine Synthesis by Iron Porphyrin Catalyzed C−H Functionalization of Indoles with Diazoacetonitrile
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journal
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February 2019 |
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Engineering new catalytic activities in enzymes
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journal
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January 2020 |
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Catalytic Asymmetric Arylation of α-Aryl-α-diazoacetates with Aniline Derivatives
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journal
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July 2015 |
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Enzymatic assembly of DNA molecules up to several hundred kilobases
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journal
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April 2009 |
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Evolutionary Origin of a Secondary Structure: π-Helices as Cryptic but Widespread Insertional Variations of α-Helices That Enhance Protein Functionality
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journal
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November 2010 |
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The medicinal chemist's toolbox for late stage functionalization of drug-like molecules
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journal
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January 2016 |
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Directed evolution of nonheme iron enzymes to access abiological radical-relay C(sp 3 )−H azidation
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journal
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May 2022 |
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An artificial metalloenzyme with the kinetics of native enzymes
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journal
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October 2016 |
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Noble−Metal Substitution in Hemoproteins: An Emerging Strategy for Abiological Catalysis
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journal
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January 2019 |
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Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization
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journal
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January 2012 |
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C–H Functionalization in organic synthesis
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journal
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January 2011 |
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Buchner and Beyond: Arene Cyclopropanation as Applied to Natural Product Total Synthesis
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journal
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October 2011 |
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A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo
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journal
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June 2013 |
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CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
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journal
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August 2012 |
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Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
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journal
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December 2018 |
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Regioselective Arene C−H Alkylation Enabled by Organic Photoredox Catalysis
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journal
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March 2020 |
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Selective Functionalization of Arene C(sp2)–H Bonds by Gold Catalysis: The Role of Carbene Substituents
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journal
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May 2022 |
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Divergent C–H Functionalizations Directed by Sulfonamide Pharmacophores: Late-Stage Diversification as a Tool for Drug Discovery
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journal
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April 2011 |
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The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid
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journal
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February 1997 |
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Enzymatic Lactone-Carbene C–H Insertion to Build Contiguous Chiral Centers
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journal
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April 2020 |
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A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry
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journal
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January 2018 |
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Abiological catalysis by artificial haem proteins containing noble metals in place of iron
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journal
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June 2016 |
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C–H Hydroxylation in Paralytic Shellfish Toxin Biosynthesis
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journal
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September 2018 |
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Chemoselective Carbophilic Addition of α‐Diazoesters through Ligand‐Controlled Gold Catalysis
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journal
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July 2014 |
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Directed evolution of RebH for catalyst-controlled halogenation of indole C–H bonds
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journal
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January 2016 |