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An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA
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journal
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November 2005 |
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Nascent peptides that block protein synthesis in bacteria
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journal
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February 2013 |
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Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics
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journal
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July 2021 |
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Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design
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journal
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June 2018 |
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N-Formyl-Methionyl-sRibonucleic Acid and Chain Initiation in Protein Biosynthesis: Polypeptidyl-sribonucleic acid and amino-acyl-sribonucleic Acid Binding Sites on Ribosomes
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journal
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July 1966 |
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Amino acid composition of proteins reduces deleterious impact of mutations
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journal
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October 2013 |
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Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70S Ribosome
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journal
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August 2009 |
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UCSF ChimeraX : Structure visualization for researchers, educators, and developers
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journal
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October 2020 |
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Translation Initiation with Initiator tRNA Charged with Exotic Peptides
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journal
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March 2009 |
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Native Chemical Ligation of Hydrolysis-Resistant 3′-Peptidyl–tRNA Mimics
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journal
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November 2011 |
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Flexizyme-catalyzed synthesis of 3′-aminoacyl-NH-tRNAs
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journal
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March 2019 |
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A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest
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journal
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July 2016 |
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Reliable semi-synthesis of hydrolysis-resistant 3′-peptidyl-tRNA conjugates containing genuine tRNA modifications
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journal
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June 2010 |
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A strategy for co-translational folding studies of ribosome-bound nascent chain complexes using NMR spectroscopy
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journal
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July 2016 |
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tRNA 3′-amino-tailing for stable amino acid attachment
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journal
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September 2018 |
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α-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel
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journal
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February 2010 |
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Macrolide antibiotics allosterically predispose the ribosome for translation arrest
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journal
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June 2014 |
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Using SecM Arrest Sequence as a Tool to Isolate Ribosome Bound Polypeptides
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journal
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June 2012 |
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Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size
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journal
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August 2016 |
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Logical engineering of D-arm and T-stem of tRNA that enhances d-amino acid incorporation
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journal
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November 2017 |
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Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation
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journal
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November 2014 |
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Free‐Radical‐Based, Specific Desulfurization of Cysteine: A Powerful Advance in the Synthesis of Polypeptides and Glycopolypeptides
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journal
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December 2007 |
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eIF5A Functions Globally in Translation Elongation and Termination
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journal
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April 2017 |
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How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis
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journal
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May 2012 |
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How Macrolide Antibiotics Work
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journal
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September 2018 |
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Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain
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journal
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March 2017 |
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Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol
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journal
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February 2022 |
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The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide
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journal
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July 2010 |
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Modulation of the Rate of Peptidyl Transfer on the Ribosome by the Nature of Substrates
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journal
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September 2008 |
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Ornithine capture by a translating ribosome controls bacterial polyamine synthesis
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journal
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February 2020 |
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Substrate Specificity of Escherichia coli Peptidyl‐Transferase
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journal
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August 1970 |
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Drop-off-reinitiation triggered by EF-G-driven mistranslocation and its alleviation by EF-P
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journal
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February 2022 |
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Molecular insights into protein synthesis with proline residues
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journal
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October 2016 |
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A two-step chemical mechanism for ribosome-catalysed peptide bond formation
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journal
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July 2011 |
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Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly
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journal
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March 2015 |
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Initiation factors IF1 and IF2 synergistically remove peptidyl-tRNAs with short polypeptides from the P-site of translating Escherichia coli ribosomes
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journal
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August 1998 |
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Rapid and efficient protein synthesis through expansion of the native chemical ligation concept
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journal
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March 2018 |
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Crystallization and preliminary X-ray analysis of Escherichia coli methionyl-tRNA Met f formyltransferase complexed with formyl-methionyl-tRNA Met f
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journal
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January 1999 |
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Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center
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journal
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October 2006 |
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An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome
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journal
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July 2017 |
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Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center
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journal
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October 2016 |
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Ribosome-targeting antibiotics and mechanisms of bacterial resistance
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journal
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December 2013 |
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Generation of ribosome nascent chain complexes for structural and functional studies
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journal
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June 2007 |
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How Widespread is Metabolite Sensing by Ribosome-Arresting Nascent Peptides?
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journal
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May 2016 |
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Arrest Peptides: Cis -Acting Modulators of Translation
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journal
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June 2013 |
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Synthesis and Aminoacylation of 3'-Amino-3'-deoxy Transfer RNA and Its Activity in Ribosomal Protein Synthesis
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journal
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September 1973 |
|
Peptide-mediated macrolide resistance reveals possible specific interactions in the nascent peptide exit tunnel: Peptide-mediated macrolide resistance
|
journal
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August 2004 |
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P−B Desulfurization: An Enabling Method for Protein Chemical Synthesis and Site‐Specific Deuteration
|
journal
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October 2017 |
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A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome
|
journal
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August 2014 |
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Important Contribution to Catalysis of Peptide Bond Formation by a Single Ionizing Group within the Ribosome
|
journal
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August 2002 |
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Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance
|
journal
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January 2021 |
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Stereochemical analysis of ribosomal transpeptidation conformation of nascent peptide
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journal
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April 1986 |
|
Ribosome release factor RF4 and termination factor RF3 are involved in dissociation of peptidyl-tRNA from the ribosome
|
journal
|
February 1998 |
|
Peptidyl transfer RNA dissociates during protein synthesis from ribosomes of Escherichia coli.
|
journal
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June 1976 |
|
The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling
|
journal
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May 2017 |
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EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues
|
journal
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December 2012 |
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Different substrate-dependent transition states in the active site of the ribosome
|
journal
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July 2011 |
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Isoleucyl-tRNA synthetase from baker's yeast and from Escherichia coli MRE 600. Discrimination of 20 amino acids in aminoacylation of tRNAIle-C-C-A(3'NH2)
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journal
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November 1987 |
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The mechanism of action of protein synthesis initiation factors from rabbit reticulocytes.
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journal
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May 1978 |
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Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches
|
journal
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December 2012 |
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Spatial Distribution and Ribosome-Binding Dynamics of EF-P in Live Escherichia coli
|
journal
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July 2017 |
|
Peptidyl transfer ribonucleic acid hydrolase activity of proteinase K
|
journal
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September 1979 |
|
Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading
|
journal
|
July 2020 |
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A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding
|
journal
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February 2016 |
|
Initiation of mammalian protein synthesis
|
journal
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November 1977 |
|
Structure of the 70S Ribosome Complexed with mRNA and tRNA
|
journal
|
September 2006 |
|
Entropic Contribution of Elongation Factor P to Proline Positioning at the Catalytic Center of the Ribosome
|
journal
|
October 2015 |
|
Purification and properties of rabbit reticulocyte protein synthesis initiation factors M2Balpha and M2Bbeta.
|
journal
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September 1976 |
|
Hypusine-containing protein eIF5A promotes translation elongation
|
journal
|
May 2009 |
|
Synthesis of proteins by native chemical ligation
|
journal
|
November 1994 |
|
The Active Site of the Ribosome Is Composed of Two Layers of Conserved Nucleotides with Distinct Roles in Peptide Bond Formation and Peptide Release
|
journal
|
May 2004 |
|
The ribosome as an entropy trap
|
journal
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May 2004 |
|
Mutational characterization and mapping of the 70S ribosome active site
|
journal
|
February 2020 |
|
Large‐scale purification of ribosome‐nascent chain complexes for biochemical and structural studies
|
journal
|
June 2009 |
|
Reevaluation of the d -Amino Acid Compatibility with the Elongation Event in Translation
|
journal
|
January 2013 |
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Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide
|
journal
|
March 2014 |