MoS 2 nanosheets effectively bind to the receptor binding domain of the SARS-CoV-2 spike protein and destabilize the spike–human ACE2 receptor interactions

Bisht, Deepali; Rath, Soumya Lipsa; Roy, Shounak; Jaiswal, Amit

doi:10.1039/d2sm01181f

MoS ₂ nanosheets effectively bind to the receptor binding domain of the SARS-CoV-2 spike protein and destabilize the spike–human ACE2 receptor interactions

Journal Article · 01 January 2022 · Soft Matter

DOI:https://doi.org/10.1039/d2sm01181f· OSTI ID:2423021

Bisht, Deepali ^[1]; ^[2]; Roy, Shounak ^[1]; ^[1]

School of Biosciences and Bioengineering, Indian Institute of Technology, Mandi, Kamand-175075, Himachal Pradesh, India
Department of Biotechnology, National Institute of Technology Warangal (NITW), Warangal -506004, Telangana, India

MoS₂nanosheet holds the potential to bind to the spike protein of SARS CoV-2 and inhibit stable spike–ACE2 interactions.

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-05CH11231

OSTI ID:: 2423021

Journal Information:: Soft Matter, Journal Name: Soft Matter Journal Issue: 47 Vol. 18; ISSN SMOABF; ISSN 1744-683X

Publisher:: Royal Society of Chemistry

Country of Publication:: United States

Language:: English

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