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Development of an 18F-labeled anti-human CD8 VHH for same-day immunoPET imaging

Journal Article · · European Journal of Nuclear Medicine and Molecular Imaging
Not provided.
Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). Advanced Light Source (ALS)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-05CH11231
OSTI ID:
2422668
Journal Information:
European Journal of Nuclear Medicine and Molecular Imaging, Journal Name: European Journal of Nuclear Medicine and Molecular Imaging Journal Issue: 3 Vol. 50; ISSN 1619-7070
Publisher:
Springer Nature
Country of Publication:
United States
Language:
English

References (39)

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Preclinical development of ZED8, an 89Zr immuno-PET reagent for monitoring tumor CD8 status in patients undergoing cancer immunotherapy journal October 2022
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CD8+ and Regulatory T cells Differentiate Tumor Immune Phenotypes and Predict Survival in Locally Advanced Head and Neck Cancer journal September 2019
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Measuring HER2-Receptor Expression In Metastatic Breast Cancer Using [68Ga]ABY-025 Affibody PET/CT journal January 2016
Structural Basis of the CD8αβ/MHC Class I Interaction: Focused Recognition Orients CD8β to a T Cell Proximal Position journal July 2009
Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies journal March 2006
Granzyme B PET Imaging as a Predictive Biomarker of Immunotherapy Response journal April 2017
Cytotoxic CD8+ T cells in cancer and cancer immunotherapy journal September 2020
Abstract LB037: 89ZED88082A PET imaging to visualize CD8+ T cells in patients with cancer treated with immune checkpoint inhibitor journal July 2021
Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care journal September 2017
Response Prediction and Evaluation Using PET in Patients with Solid Tumors Treated with Immunotherapy journal June 2021
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Biophysical Properties of Camelid VHH Domains Compared to Those of Human VH3 Domains journal February 2002
89Zr-PET imaging in humans: a systematic review journal September 2021
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