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Identification of 2-Hydroxyacyl-CoA Synthases with High Acyloin Condensation Activity for Orthogonal One-Carbon Bioconversion

Journal Article · · ACS Catalysis
 [1];  [2];  [3];  [2];  [2];  [3];  [4];  [2]
  1. Department of Chemical, Biological, and Materials Engineering, University of South Florida, Tampa, Florida 33620, United States; OSTI
  2. Department of Chemical, Biological, and Materials Engineering, University of South Florida, Tampa, Florida 33620, United States
  3. Department of Biochemistry and Synthetic Metabolism, Max-Planck-Institute for Terrestrial Microbiology, 35043 Marburg, Germany
  4. Department of Biochemistry and Synthetic Metabolism, Max-Planck-Institute for Terrestrial Microbiology, 35043 Marburg, Germany; Center for Synthetic Microbiology (SYNMIKRO), 35032 Marburg, Germany
Not provided.
Research Organization:
Montana State Univ., Bozeman, MT (United States); Univ. of California, Oakland, CA (United States)
Sponsoring Organization:
USDOE Office of Energy Efficiency and Renewable Energy (EERE)
DOE Contract Number:
EE0008499; AC02-05CH11231
OSTI ID:
2418631
Journal Information:
ACS Catalysis, Journal Name: ACS Catalysis Journal Issue: 18 Vol. 13; ISSN 2155-5435
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
English

References (50)

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction journal October 1953
A modified serine cycle in Escherichia coli coverts methanol and CO2 to two-carbon compounds journal September 2018
Basic local alignment search tool journal October 1990
An orthogonal metabolic framework for one-carbon utilization journal October 2021
2-Hydroxyacyl-CoA lyase catalyzes acyloin condensation for one-carbon bioconversion journal August 2019
Actinobacterial Degradation of 2-Hydroxyisobutyric Acid Proceeds via Acetone and Formyl-CoA by Employing a Thiamine-Dependent Lyase Reaction journal April 2020
Reverse β-oxidation pathways for efficient chemical production journal February 2022
The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways journal September 2019
Synthetic metabolism: metabolic engineering meets enzyme design journal April 2017
Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale journal February 2022
Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation journal April 2021
Mechanistic details of the actinobacterial lyase-catalyzed degradation reaction of 2-hydroxyisobutyryl-CoA journal January 2022
The reductive glycine pathway allows autotrophic growth of Desulfovibrio desulfuricans journal October 2020
Synthetic or natural? Metabolic engineering for assimilation and valorization of methanol journal April 2022
Development of a kinetic model and figures of merit for formaldehyde carboligations catalyzed by formolase enzymes journal September 2022
Ruthenium-Catalyzed Reduction of Carbon Dioxide to Formaldehyde journal March 2014
Catalytic efficiency and kcat/KM: a useful comparator? journal June 2007
Polyketide biosynthesis: a millennium review journal January 2001
Promises of Main Group Metal–Based Nanostructured Materials for Electrochemical CO 2 Reduction to Formate journal November 2019
Conversion of Escherichia coli to Generate All Biomass Carbon from CO2 journal November 2019
Enzymology of the Wood-Ljungdahl Pathway of Acetogenesis journal March 2008
Culture Medium for Enterobacteria journal January 1974
Formate Assimilation: The Metabolic Architecture of Natural and Synthetic Pathways journal July 2016
Ionic Liquid-Mediated Selective Conversion of CO2 to CO at Low Overpotentials journal September 2011
Escherichia coli as a host for metabolic engineering journal November 2018
The I-TASSER Suite: protein structure and function prediction journal December 2014
IVA cloning: A single-tube universal cloning system exploiting bacterial In Vivo Assembly journal June 2016
Cell-free chemoenzymatic starch synthesis from carbon dioxide journal September 2021
Crystallographic Snapshots of Oxalyl-CoA Decarboxylase Give Insights into Catalysis by Nonoxidative ThDP-Dependent Decarboxylases journal July 2007
Engineering Escherichia coli to synthesize free fatty acids journal December 2012
Developing reactors for electrifying bio-methanation: a perspective from bio-electrochemistry journal January 2022
Computational protein design enables a novel one-carbon assimilation pathway journal March 2015
Engineering a Highly Efficient Carboligase for Synthetic One-Carbon Metabolism journal April 2021
Combinatorial alanine-scanning journal June 2001
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks journal November 2003
Highly accurate protein structure prediction with AlphaFold journal July 2021
Saccharomyces cerevisiae and its industrial applications journal January 2020
CD-HIT Suite: a web server for clustering and comparing biological sequences journal January 2010
Growth of E. coli on formate and methanol via the reductive glycine pathway journal February 2020
One-pot chemoenzymatic synthesis of glycolic acid from formaldehyde journal January 2022
Enzyme engineering and in vivo testing of a formate reduction pathway journal September 2021
ColabFold: making protein folding accessible to all journal May 2022
Multilayer Engineering of an Escherichia coli-Based Biotransformation System to Exclusively Produce Glycolic Acid from Formaldehyde journal January 2023
Converting Escherichia coli to a Synthetic Methylotroph Growing Solely on Methanol journal August 2020
Recent developments on heterogeneous catalytic CO2 reduction to methanol journal December 2019
Glyoxylate carboligase-based whole-cell biotransformation of formaldehyde into ethylene glycol via glycolaldehyde journal January 2022
Replacing the Calvin cycle with the reductive glycine pathway in Cupriavidus necator journal November 2020
Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo journal May 2023
Constructing a synthetic pathway for acetyl-coenzyme A from one-carbon through enzyme design journal March 2019
Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle journal September 2022

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