Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet-printed CNT Electrodes-droplet Based Paracetamol Detection in Biological Fluids for “Point-of-care” Applications

Journal Article · Mon Jul 01 00:00:00 EDT 2019 · Electroanalysis

DOI:https://doi.org/10.1002/ELAN.201900129· OSTI ID:22946900

Stanković, Dalibor M.; Ognjanović, Miloš; Jović, Milica; Cuplić, Valentina; Lesch, Andreas; others, and

A disposable acetaminophen biosensor based on inkjet-printed CNT electrodes (IJPCNT) modified with amidase/cerium dioxide@graphene nanoribbons composite was developed (ACeO2@GNR/IJPCNT). The enzyme amidase A was used for the first time as a recognition element. Inkjet-printed CNT electrodes served as a basis for the construction of a biosensor that enables droplet detection using 5 μL sample volume. The biosensor showed high selectivity, sensitivity, a low detection limit of 0.18 μM and a wide working linear range from 1 to 100 μM. The proposed approach allows fast and reliable detection of acetaminophen in biological fluids with negligible matrix effect and remarkable reproducibility. © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

• OSTI ID: 22946900
• Journal Information: Electroanalysis, Vol. 31, Issue 8; Other Information: OAI: vinar.vin.bg.ac.rs:123456789/8342; Country of input: Serbia; ISSN 1040-0397
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
60 APPLIED LIFE SCIENCES
AMIDASES
BASES
BODY FLUIDS
CARBON MONOXIDE
CERIUM OXIDES
DETECTION
DROPLETS
ELECTRODES
GRAPHENE