Simultaneous Improvement of Resolving Power and Signal-to-Noise Ratio Using a Modified Hadamard Transform-Inverse Ion Mobility Spectrometry Technique
- Chinese Academy of Sciences, Anhui Province Key Laboratory of Medical Physics and Technology, Center of Medical Physics and Technology, Hefei Institutes of Physical Science (China)
- Huaibei Normal University, College of Computer Science and Technology (China)
In order to improve the resolving power (RP) and signal-to-noise ratio (SNR) of ion mobility spectrometry (IMS) simultaneously, a modified Hadamard transform-inverse ion mobility spectrometry (MHT-IIMS) technique was developed. In this novel technique, a series of isolating codes were appended to each element of the pseudo random binary sequence (PRBS), and then the modified modulation sequence was formed and used to control the ion gate of the inverse IMS (IIMS). Experimental results demonstrate that the MHT-IIMS technique can significantly enhance the resolving power and SNR simultaneously by measuring the spectra of reaction ions. Furthermore, the gas sample CCl{sub 4} and CHCl{sub 3} were measured for evaluating the capability of detecting those samples which have single and multiple product ions. The results show that this novel technique is able to simultaneously improve the resolving power and SNR notablely for the real sample detection without any significant instrumental changes. .
- OSTI ID:
- 22776827
- Journal Information:
- Journal of the American Society for Mass Spectrometry, Vol. 28, Issue 11; Other Information: Copyright (c) 2017 American Society for Mass Spectrometry; http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 1044-0305
- Country of Publication:
- United States
- Language:
- English
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