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Title: Magnetic Performance and Evaluation of Radiofrequency Hyperthermia of Perovskite La{sub 1−x}Sr{sub x}MnO{sub 3}

Abstract

Magnetic nanoparticles (MNPs) can induce localized hyperthermia by alternating magnetic fields, in order to kill cells at tumor sites. In this study, La{sub 1−x}Sr{sub x}MnO{sub 3} nanoparticles with x = 0.2, 0.3, 0.4, and 0.5 were prepared via sol–gel technique. The synthesized nanoparticles were characterized in terms of structure, morphology, and magnetic properties with Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and vibrating sample magnetometer (VSM) studies. The average size of nanoparticles was measured to be 57.09, 30.477, 10.24, and 35.982 nm by Williamson–Hall method for x = 0.2, 0.3, 0.4, and 0.5, respectively. The absence of hysteresis in the magnetic response of nanoparticles represents the superparamagnetic behavior. Toxicity test was also performed to evaluate the toxicity concerns of the prepared nanoparticles upon entrance to the body. Furthermore, the alternating current magnetic heating characteristics of La{sub 1−x}Sr{sub x}MnO{sub 3} nanoparticles was also studied, by 1 mg/mL concentration, to test the ability of the nanoparticles as magnetic hyperthermia treatment agents. The magnetothermia were measured in an RF magnetic field of 88 Oe and 430 kHz. The present work reveals that LSMO nanoparticles possess the biocompatible properties for biomedical applications and can provide the required heatmore » at appropriate time.« less

Authors:
; ; ;  [1]
  1. University of Mazandaran, Department of Solid State Physics (Iran, Islamic Republic of)
Publication Date:
OSTI Identifier:
22773968
Resource Type:
Journal Article
Journal Name:
Journal of Superconductivity and Novel Magnetism
Additional Journal Information:
Journal Volume: 31; Journal Issue: 7; Other Information: Copyright (c) 2018 Springer Science+Business Media, LLC, part of Springer Nature; http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 1557-1939
Country of Publication:
United States
Language:
English
Subject:
75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; FOURIER TRANSFORM SPECTROMETERS; HEATING; HYPERTHERMIA; HYSTERESIS; INFRARED SPECTRA; LANTHANUM COMPOUNDS; MAGNETIC FIELDS; MAGNETIC PROPERTIES; MANGANATES; MANGANESE PHOSPHIDES; MORPHOLOGY; NANOPARTICLES; NEOPLASMS; PEROVSKITES; RADIOWAVE RADIATION; SCANNING ELECTRON MICROSCOPY; SOL-GEL PROCESS; SUPERPARAMAGNETISM; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY; VIBRATING SAMPLE MAGNETOMETERS; X-RAY DIFFRACTION

Citation Formats

Lotfi, Sheida, Bahari, Saeedeh, Bahari, Ali, and Roudbari, Mandana. Magnetic Performance and Evaluation of Radiofrequency Hyperthermia of Perovskite La{sub 1−x}Sr{sub x}MnO{sub 3}. United States: N. p., 2018. Web. doi:10.1007/S10948-017-4475-9.
Lotfi, Sheida, Bahari, Saeedeh, Bahari, Ali, & Roudbari, Mandana. Magnetic Performance and Evaluation of Radiofrequency Hyperthermia of Perovskite La{sub 1−x}Sr{sub x}MnO{sub 3}. United States. doi:10.1007/S10948-017-4475-9.
Lotfi, Sheida, Bahari, Saeedeh, Bahari, Ali, and Roudbari, Mandana. Sun . "Magnetic Performance and Evaluation of Radiofrequency Hyperthermia of Perovskite La{sub 1−x}Sr{sub x}MnO{sub 3}". United States. doi:10.1007/S10948-017-4475-9.
@article{osti_22773968,
title = {Magnetic Performance and Evaluation of Radiofrequency Hyperthermia of Perovskite La{sub 1−x}Sr{sub x}MnO{sub 3}},
author = {Lotfi, Sheida and Bahari, Saeedeh and Bahari, Ali and Roudbari, Mandana},
abstractNote = {Magnetic nanoparticles (MNPs) can induce localized hyperthermia by alternating magnetic fields, in order to kill cells at tumor sites. In this study, La{sub 1−x}Sr{sub x}MnO{sub 3} nanoparticles with x = 0.2, 0.3, 0.4, and 0.5 were prepared via sol–gel technique. The synthesized nanoparticles were characterized in terms of structure, morphology, and magnetic properties with Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and vibrating sample magnetometer (VSM) studies. The average size of nanoparticles was measured to be 57.09, 30.477, 10.24, and 35.982 nm by Williamson–Hall method for x = 0.2, 0.3, 0.4, and 0.5, respectively. The absence of hysteresis in the magnetic response of nanoparticles represents the superparamagnetic behavior. Toxicity test was also performed to evaluate the toxicity concerns of the prepared nanoparticles upon entrance to the body. Furthermore, the alternating current magnetic heating characteristics of La{sub 1−x}Sr{sub x}MnO{sub 3} nanoparticles was also studied, by 1 mg/mL concentration, to test the ability of the nanoparticles as magnetic hyperthermia treatment agents. The magnetothermia were measured in an RF magnetic field of 88 Oe and 430 kHz. The present work reveals that LSMO nanoparticles possess the biocompatible properties for biomedical applications and can provide the required heat at appropriate time.},
doi = {10.1007/S10948-017-4475-9},
journal = {Journal of Superconductivity and Novel Magnetism},
issn = {1557-1939},
number = 7,
volume = 31,
place = {United States},
year = {2018},
month = {7}
}