skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Absolute Configuration of Andrographolide and Its Proliferation of Osteoblast Cell Lines

Abstract

Andrographolide, C{sub 20}H{sub 30}O{sub 5}, is a labdane diterpenoid which was isolated from the leave of Andrographis paniculata. Its crystal structure is determined by single crystal X-ray diffraction: monoclinic, sp. gr. P2{sub 1}, Z = 2. Absolute configuration is determined by the refinement of the Flack parameter to 0.21(19). In the crystal, molecules are linked by O–H···O hydrogen bonds and C–H···O interactions into two dimensional network parallel to the (001) plane. Its proliferation of osteoblast cell lines is reported.

Authors:
 [1];  [2]; ;  [3];  [4];  [5]
  1. Prince of Songkla University, Department of Chemistry, Faculty of Science (Thailand)
  2. Thaksin University, Department of Basic Science and Mathematics, Faculty of Science (Thailand)
  3. Prince of Songkla University, Department of Biochemistry, Faculty of Science (Thailand)
  4. Visvesvaraya Technological University, Alanahalli, Department of Engineering Chemistry, Vidya Vikas Institute of Engineering and Technology (India)
  5. Universiti Sains Malaysia, X-ray Crystallography Unit, School of Physics (Malaysia)
Publication Date:
OSTI Identifier:
22758238
Resource Type:
Journal Article
Journal Name:
Crystallography Reports
Additional Journal Information:
Journal Volume: 63; Journal Issue: 3; Other Information: Copyright (c) 2018 Pleiades Publishing, Inc.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 1063-7745
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 60 APPLIED LIFE SCIENCES; CELL PROLIFERATION; CONNECTIVE TISSUE CELLS; HYDROGEN; INTERACTIONS; MOLECULES; MONOCLINIC LATTICES; MONOCRYSTALS; TWO-DIMENSIONAL SYSTEMS; X-RAY DIFFRACTION

Citation Formats

Chantrapromma, S., E-mail: suchada-3p@hotmail.com, Boonnak, N., E-mail: nawongb@yahoo.com, Pitakpornpreecha, T., Yordthong, T., Chidan Kumar, C. S., and Fun, H. K. Absolute Configuration of Andrographolide and Its Proliferation of Osteoblast Cell Lines. United States: N. p., 2018. Web. doi:10.1134/S1063774518030069.
Chantrapromma, S., E-mail: suchada-3p@hotmail.com, Boonnak, N., E-mail: nawongb@yahoo.com, Pitakpornpreecha, T., Yordthong, T., Chidan Kumar, C. S., & Fun, H. K. Absolute Configuration of Andrographolide and Its Proliferation of Osteoblast Cell Lines. United States. doi:10.1134/S1063774518030069.
Chantrapromma, S., E-mail: suchada-3p@hotmail.com, Boonnak, N., E-mail: nawongb@yahoo.com, Pitakpornpreecha, T., Yordthong, T., Chidan Kumar, C. S., and Fun, H. K. Tue . "Absolute Configuration of Andrographolide and Its Proliferation of Osteoblast Cell Lines". United States. doi:10.1134/S1063774518030069.
@article{osti_22758238,
title = {Absolute Configuration of Andrographolide and Its Proliferation of Osteoblast Cell Lines},
author = {Chantrapromma, S., E-mail: suchada-3p@hotmail.com and Boonnak, N., E-mail: nawongb@yahoo.com and Pitakpornpreecha, T. and Yordthong, T. and Chidan Kumar, C. S. and Fun, H. K.},
abstractNote = {Andrographolide, C{sub 20}H{sub 30}O{sub 5}, is a labdane diterpenoid which was isolated from the leave of Andrographis paniculata. Its crystal structure is determined by single crystal X-ray diffraction: monoclinic, sp. gr. P2{sub 1}, Z = 2. Absolute configuration is determined by the refinement of the Flack parameter to 0.21(19). In the crystal, molecules are linked by O–H···O hydrogen bonds and C–H···O interactions into two dimensional network parallel to the (001) plane. Its proliferation of osteoblast cell lines is reported.},
doi = {10.1134/S1063774518030069},
journal = {Crystallography Reports},
issn = {1063-7745},
number = 3,
volume = 63,
place = {United States},
year = {2018},
month = {5}
}