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Title: Structure of Sodium Cholate Micelles

Abstract

Sodium cholate is a bile acid salt, which is applied as a biological detergent. The mixed systems of phospholipid/sodium cholate are used to study the self-assembly of micelles and formation of micellar systems. The micelles consisting of a phospholipid/sodium cholate mixture are used for drug delivery through the skin. An important part of the investigations in this field is examination of the structure and properties of micelles consisting of sodium cholate molecules. The structure of sodium cholate micelles have been investigated by small-angle neutron scattering. The average radius of sodium cholate micelles in the sodium cholate concentration range of 25‒100 mM is found to be 10.14 ± 0.01 Å.

Authors:
;  [1]
  1. Joint Institute for Nuclear Research, Laboratory of Neutron Physics (Russian Federation)
Publication Date:
OSTI Identifier:
22758231
Resource Type:
Journal Article
Journal Name:
Crystallography Reports
Additional Journal Information:
Journal Volume: 63; Journal Issue: 3; Other Information: Copyright (c) 2018 Pleiades Publishing, Inc.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 1063-7745
Country of Publication:
United States
Language:
English
Subject:
75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; BILE ACIDS; CONCENTRATION RATIO; DRUG DELIVERY; MICELLAR SYSTEMS; MIXTURES; MOLECULES; NEUTRON DIFFRACTION; PHOSPHOLIPIDS; SALTS; SKIN; SMALL ANGLE SCATTERING; SODIUM

Citation Formats

Maslova, V. A., E-mail: Varya.Maslova@yandex.ru, and Kiselev, M. A. Structure of Sodium Cholate Micelles. United States: N. p., 2018. Web. doi:10.1134/S1063774518030173.
Maslova, V. A., E-mail: Varya.Maslova@yandex.ru, & Kiselev, M. A. Structure of Sodium Cholate Micelles. United States. doi:10.1134/S1063774518030173.
Maslova, V. A., E-mail: Varya.Maslova@yandex.ru, and Kiselev, M. A. Tue . "Structure of Sodium Cholate Micelles". United States. doi:10.1134/S1063774518030173.
@article{osti_22758231,
title = {Structure of Sodium Cholate Micelles},
author = {Maslova, V. A., E-mail: Varya.Maslova@yandex.ru and Kiselev, M. A.},
abstractNote = {Sodium cholate is a bile acid salt, which is applied as a biological detergent. The mixed systems of phospholipid/sodium cholate are used to study the self-assembly of micelles and formation of micellar systems. The micelles consisting of a phospholipid/sodium cholate mixture are used for drug delivery through the skin. An important part of the investigations in this field is examination of the structure and properties of micelles consisting of sodium cholate molecules. The structure of sodium cholate micelles have been investigated by small-angle neutron scattering. The average radius of sodium cholate micelles in the sodium cholate concentration range of 25‒100 mM is found to be 10.14 ± 0.01 Å.},
doi = {10.1134/S1063774518030173},
journal = {Crystallography Reports},
issn = {1063-7745},
number = 3,
volume = 63,
place = {United States},
year = {2018},
month = {5}
}