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Title: The Value of Hybrid Angio-CT in Preoperative Detection and Localization of Insulinomas: A Single-Center Retrospective Study

Abstract

ObjectiveTo investigate the performance of hybrid angio-CT in preoperative detection and localization for insulinomas.MethodsFifty-four postoperative pathology-confirmed patients from April 2015 to March 2017 were retrospectively reviewed; all patients underwent angio-CT with administration of contrast media in SMA, GDA and SA due to negative, inconclusive or controversial findings by several preoperative diagnostic methods including TAUS, CEUS, EUS, ECT, EMRI and DSA. Surgery was used as gold standard for localization of insulinomas; detection sensitivity and localization accuracy of angio-CT were assessed and compared with other preoperative image options.ResultsFifty-six benign insulinomas (mean diameter, 15.8 mm) in 54 patients (18 men and 36 women) were found according to surgical results; the overall detection sensitivity of TAUS, CEUS, EUS, ECT, EMRI and DSA was 21.4, 78.4, 79.2, 70.0, 79.2 and 72.2%, respectively. The overall localization accuracy was 14.3, 58.8, 68.8, 60.0, 75.0 and 44.4%, respectively. A total of 53 tumors were detected by angio-CT, 51 tumors were accurately located, and the overall detection sensitivity and localization accuracy of angio-CT was 94.4 and 90.7%, which was significantly higher than that of all other preoperative diagnostic methods (p < 0.05). No any serious complications occurred during angio-CT.ConclusionOur study indicates the great potential value of angio-CT in the preoperative detection andmore » localization of insulinomas; angio-CT can be used as a preferred invasive diagnostic method.« less

Authors:
; ; ; ;  [1];  [2]; ;  [1]
  1. Chinese PLA General Hospital, Department of Interventional Radiology (China)
  2. Nankai University, School of Medicine (China)
Publication Date:
OSTI Identifier:
22750082
Resource Type:
Journal Article
Journal Name:
Cardiovascular and Interventional Radiology
Additional Journal Information:
Journal Volume: 41; Journal Issue: 4; Other Information: Copyright (c) 2018 Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CONTRAST MEDIA; EUROPIUM SULFIDES; HYBRIDIZATION; IMAGE PROCESSING; NEOPLASMS; PATIENTS; RADIOSENSITIVITY

Citation Formats

Fu, Jinxin, Liu, Fengyong, Yuan, Kai, Yan, Jieyu, Wang, Yan, Zhang, Jinlong, Yuan, Bing, and Wang, Maoqiang. The Value of Hybrid Angio-CT in Preoperative Detection and Localization of Insulinomas: A Single-Center Retrospective Study. United States: N. p., 2018. Web. doi:10.1007/S00270-017-1847-2.
Fu, Jinxin, Liu, Fengyong, Yuan, Kai, Yan, Jieyu, Wang, Yan, Zhang, Jinlong, Yuan, Bing, & Wang, Maoqiang. The Value of Hybrid Angio-CT in Preoperative Detection and Localization of Insulinomas: A Single-Center Retrospective Study. United States. doi:10.1007/S00270-017-1847-2.
Fu, Jinxin, Liu, Fengyong, Yuan, Kai, Yan, Jieyu, Wang, Yan, Zhang, Jinlong, Yuan, Bing, and Wang, Maoqiang. Sun . "The Value of Hybrid Angio-CT in Preoperative Detection and Localization of Insulinomas: A Single-Center Retrospective Study". United States. doi:10.1007/S00270-017-1847-2.
@article{osti_22750082,
title = {The Value of Hybrid Angio-CT in Preoperative Detection and Localization of Insulinomas: A Single-Center Retrospective Study},
author = {Fu, Jinxin and Liu, Fengyong and Yuan, Kai and Yan, Jieyu and Wang, Yan and Zhang, Jinlong and Yuan, Bing and Wang, Maoqiang},
abstractNote = {ObjectiveTo investigate the performance of hybrid angio-CT in preoperative detection and localization for insulinomas.MethodsFifty-four postoperative pathology-confirmed patients from April 2015 to March 2017 were retrospectively reviewed; all patients underwent angio-CT with administration of contrast media in SMA, GDA and SA due to negative, inconclusive or controversial findings by several preoperative diagnostic methods including TAUS, CEUS, EUS, ECT, EMRI and DSA. Surgery was used as gold standard for localization of insulinomas; detection sensitivity and localization accuracy of angio-CT were assessed and compared with other preoperative image options.ResultsFifty-six benign insulinomas (mean diameter, 15.8 mm) in 54 patients (18 men and 36 women) were found according to surgical results; the overall detection sensitivity of TAUS, CEUS, EUS, ECT, EMRI and DSA was 21.4, 78.4, 79.2, 70.0, 79.2 and 72.2%, respectively. The overall localization accuracy was 14.3, 58.8, 68.8, 60.0, 75.0 and 44.4%, respectively. A total of 53 tumors were detected by angio-CT, 51 tumors were accurately located, and the overall detection sensitivity and localization accuracy of angio-CT was 94.4 and 90.7%, which was significantly higher than that of all other preoperative diagnostic methods (p < 0.05). No any serious complications occurred during angio-CT.ConclusionOur study indicates the great potential value of angio-CT in the preoperative detection and localization of insulinomas; angio-CT can be used as a preferred invasive diagnostic method.},
doi = {10.1007/S00270-017-1847-2},
journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 4,
volume = 41,
place = {United States},
year = {2018},
month = {4}
}