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Title: MO-FG-CAMPUS-IeP2-03: Validation of an SSDE-To-Organ-Dose Calculation Methodology Developed for Pediatric CT in An Adult Population

Abstract

Purpose: To discover if a previously published methodology for estimating patient-specific organ dose in a pediatric population (5–55kg) is translatable to the adult sized patient population (> 55 kg). Methods: An adult male anthropomorphic phantom was scanned with metal oxide semiconductor field effect transistor (MOSFET) dosimeters placed at 23 organ locations in the chest and abdominopelvic regions to determine absolute organ dose. Organ-dose-to-SSDE correlation factors were developed by dividing individual phantom organ doses by SSDE of the phantom; where SSDE was calculated at the center of the scan volume of the chest and abdomen/pelvis separately. Organ dose correlation factors developed in phantom were multiplied by 28 chest and 22 abdominopelvic patient SSDE values to estimate organ dose. The median patient weight from the CT examinations was 68.9 kg (range 57–87 kg) and median age was 17 years (range 13–28 years). Calculated organ dose estimates were compared to published Monte Carlo simulated patient and phantom results. Results: Organ-dose-to-SSDE correlation was determined for a total of 23 organs in the chest and abdominopelvic regions. For organs fully covered by the scan volume, correlation in the chest (median 1.3; range 1.1–1.5) and abdominopelvic (median 0.9; range 0.7–1.0) was 1.0 ± 10%. For organsmore » that extended beyond the scan volume (i.e. skin bone marrow and bone surface) correlation was determined to be a median of 0.3 (range 0.1–0.4). Calculated patient organ dose using patient SSDE agreed to better than 6% (chest) and 15% (abdominopelvic) to published values. Conclusion: This study demonstrated that our previous published methodology for calculating organ dose using patient-specific SSDE for the chest and abdominopelvic regions is translatable to adult sized patients for organs fully covered by the scan volume.« less

Authors:
 [1];  [2]; ;  [3]
  1. Christian Brothers University, Memphis, TN (United States)
  2. (United States)
  3. St. Jude Children’s Research Hospital, Memphis, TN (United States)
Publication Date:
OSTI Identifier:
22653899
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 43; Journal Issue: 6; Other Information: (c) 2016 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; ADULTS; BONE MARROW; CHEST; COMPUTERIZED TOMOGRAPHY; CORRELATIONS; MONTE CARLO METHOD; OXIDES; PATIENTS; PEDIATRICS; PHANTOMS; RADIATION DOSES

Citation Formats

Mead, H, St. Jude Children’s Research Hospital, Memphis, TN, Brady, S, and Kaufman, R. MO-FG-CAMPUS-IeP2-03: Validation of an SSDE-To-Organ-Dose Calculation Methodology Developed for Pediatric CT in An Adult Population. United States: N. p., 2016. Web. doi:10.1118/1.4957351.
Mead, H, St. Jude Children’s Research Hospital, Memphis, TN, Brady, S, & Kaufman, R. MO-FG-CAMPUS-IeP2-03: Validation of an SSDE-To-Organ-Dose Calculation Methodology Developed for Pediatric CT in An Adult Population. United States. doi:10.1118/1.4957351.
Mead, H, St. Jude Children’s Research Hospital, Memphis, TN, Brady, S, and Kaufman, R. Wed . "MO-FG-CAMPUS-IeP2-03: Validation of an SSDE-To-Organ-Dose Calculation Methodology Developed for Pediatric CT in An Adult Population". United States. doi:10.1118/1.4957351.
@article{osti_22653899,
title = {MO-FG-CAMPUS-IeP2-03: Validation of an SSDE-To-Organ-Dose Calculation Methodology Developed for Pediatric CT in An Adult Population},
author = {Mead, H and St. Jude Children’s Research Hospital, Memphis, TN and Brady, S and Kaufman, R},
abstractNote = {Purpose: To discover if a previously published methodology for estimating patient-specific organ dose in a pediatric population (5–55kg) is translatable to the adult sized patient population (> 55 kg). Methods: An adult male anthropomorphic phantom was scanned with metal oxide semiconductor field effect transistor (MOSFET) dosimeters placed at 23 organ locations in the chest and abdominopelvic regions to determine absolute organ dose. Organ-dose-to-SSDE correlation factors were developed by dividing individual phantom organ doses by SSDE of the phantom; where SSDE was calculated at the center of the scan volume of the chest and abdomen/pelvis separately. Organ dose correlation factors developed in phantom were multiplied by 28 chest and 22 abdominopelvic patient SSDE values to estimate organ dose. The median patient weight from the CT examinations was 68.9 kg (range 57–87 kg) and median age was 17 years (range 13–28 years). Calculated organ dose estimates were compared to published Monte Carlo simulated patient and phantom results. Results: Organ-dose-to-SSDE correlation was determined for a total of 23 organs in the chest and abdominopelvic regions. For organs fully covered by the scan volume, correlation in the chest (median 1.3; range 1.1–1.5) and abdominopelvic (median 0.9; range 0.7–1.0) was 1.0 ± 10%. For organs that extended beyond the scan volume (i.e. skin bone marrow and bone surface) correlation was determined to be a median of 0.3 (range 0.1–0.4). Calculated patient organ dose using patient SSDE agreed to better than 6% (chest) and 15% (abdominopelvic) to published values. Conclusion: This study demonstrated that our previous published methodology for calculating organ dose using patient-specific SSDE for the chest and abdominopelvic regions is translatable to adult sized patients for organs fully covered by the scan volume.},
doi = {10.1118/1.4957351},
journal = {Medical Physics},
number = 6,
volume = 43,
place = {United States},
year = {Wed Jun 15 00:00:00 EDT 2016},
month = {Wed Jun 15 00:00:00 EDT 2016}
}