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Title: SU-G-IeP2-13: Toward Heavy Ion Computed Tomography with Carbon Ions: A Monte Carlo Study

Abstract

Purpose: In the present Monte Carlo study, we investigated the use of Carbon ions for computed tomography (CT) with a relatively low imaging dose. This will enable us to avoid any conversion of X-ray CT numbers to the relative stopping power (or relative electron density) values and the associated uncertainties in Carbon dose calculation. Methods: In the first stage, we studied the propagation of Carbon nuclei through a water phantom using the Geant4 specially to understand their lateral displacement inside the phantom. In the second stage, we used our GPU-based Monte Carlo code, which has been cross validated against Geant4, to create the 2D map of the water equivalent path length (WEPL) inside a human head size phantom by acquiring 240 projections each 1.5° apart. Subsequently the 3D relative electron density map of the phantom was reconstructed from the 2D WEPL map using the Algebraic Reconstruction Technique (ART) coupled with total variation (TV) minimization Results: A high quality image of the relative electron density inside the phantom was reconstructed by ARTTV. The mean relative error between the reconstructed image for low contrast object (PMMA) was about 1.74%. The delivered dose per scan at the center of the phantom was aboutmore » 0.1 Gy. Conclusion: We have been able to obtain a 3D map of the electron density using a human head size phantom while keeping the delivered dose to relatively low value. Using the GPU capabilities of our simulation engine, we believe that a real time CT with Carbon ions could be a reality in future.« less

Authors:
; ; ; ;  [1]
  1. UT Southwestern Medical Center, Dallas, TX (United States)
Publication Date:
OSTI Identifier:
22649365
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 43; Journal Issue: 6; Other Information: (c) 2016 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 61 RADIATION PROTECTION AND DOSIMETRY; BIOMEDICAL RADIOGRAPHY; CARBON IONS; COMPUTERIZED TOMOGRAPHY; ELECTRON DENSITY; HEAVY IONS; IMAGES; MONTE CARLO METHOD; PHANTOMS; RADIATION DOSES; X RADIATION

Citation Formats

Shrestha, D, Qin, N, Zhang, Y, Jia, X, and Wang, J. SU-G-IeP2-13: Toward Heavy Ion Computed Tomography with Carbon Ions: A Monte Carlo Study. United States: N. p., 2016. Web. doi:10.1118/1.4957018.
Shrestha, D, Qin, N, Zhang, Y, Jia, X, & Wang, J. SU-G-IeP2-13: Toward Heavy Ion Computed Tomography with Carbon Ions: A Monte Carlo Study. United States. doi:10.1118/1.4957018.
Shrestha, D, Qin, N, Zhang, Y, Jia, X, and Wang, J. Wed . "SU-G-IeP2-13: Toward Heavy Ion Computed Tomography with Carbon Ions: A Monte Carlo Study". United States. doi:10.1118/1.4957018.
@article{osti_22649365,
title = {SU-G-IeP2-13: Toward Heavy Ion Computed Tomography with Carbon Ions: A Monte Carlo Study},
author = {Shrestha, D and Qin, N and Zhang, Y and Jia, X and Wang, J},
abstractNote = {Purpose: In the present Monte Carlo study, we investigated the use of Carbon ions for computed tomography (CT) with a relatively low imaging dose. This will enable us to avoid any conversion of X-ray CT numbers to the relative stopping power (or relative electron density) values and the associated uncertainties in Carbon dose calculation. Methods: In the first stage, we studied the propagation of Carbon nuclei through a water phantom using the Geant4 specially to understand their lateral displacement inside the phantom. In the second stage, we used our GPU-based Monte Carlo code, which has been cross validated against Geant4, to create the 2D map of the water equivalent path length (WEPL) inside a human head size phantom by acquiring 240 projections each 1.5° apart. Subsequently the 3D relative electron density map of the phantom was reconstructed from the 2D WEPL map using the Algebraic Reconstruction Technique (ART) coupled with total variation (TV) minimization Results: A high quality image of the relative electron density inside the phantom was reconstructed by ARTTV. The mean relative error between the reconstructed image for low contrast object (PMMA) was about 1.74%. The delivered dose per scan at the center of the phantom was about 0.1 Gy. Conclusion: We have been able to obtain a 3D map of the electron density using a human head size phantom while keeping the delivered dose to relatively low value. Using the GPU capabilities of our simulation engine, we believe that a real time CT with Carbon ions could be a reality in future.},
doi = {10.1118/1.4957018},
journal = {Medical Physics},
issn = {0094-2405},
number = 6,
volume = 43,
place = {United States},
year = {2016},
month = {6}
}